Table 1.
Hematological toxicity according to NCI-CTC
| Type of toxicity | Group A | Group B | |||
|---|---|---|---|---|---|
| n | % | n | % | ||
| Anemia | |||||
| Grade I | 52 | 34% | 69 | 46% | 0.021* |
| Grade II | 11 | 7.3% | 26 | 17.3% | 0.032* |
| Grade III | 13 | 8.6% | 11 | 7.3% | 0.064 |
| Grade IV | 4 | 2.6% | 7 | 4.6% | 0.027* |
| Leucopoenia | |||||
| Grade I | 3 | 2% | 11 | 7.3% | 0.032* |
| Grade II | 7 | 4.6% | 8 | 5.3% | 0.046* |
| Grade III | 4 | 2.6% | 4 | 2.6% | 0.018* |
| Grade IV | 1 | 0.6% | 4 | 2.6% | 0.019* |
| Thrombocytopenia | |||||
| Grade I | 13 | 8.6% | 9 | 6% | 0.062 |
| Grade II | 10 | 6.6% | 8 | 5.3% | 0.069 |
| Grade III | 4 | 2.6% | 2 | 1.3% | 0.065 |
| Grade IV | 0 | 3 | 2% | 0.047* | |
| Neutropenia | |||||
| Grade I | 2 | 1.3% | 7 | 4.6% | 0.031* |
| Grade II | 17 | 11.3% | 14 | 9.3% | 0.071 |
| Grade III | 5 | 3.3% | 8 | 5.3% | 0.034* |
| Grade IV | 1 | 0.6% | 8 | 5.3% | 0.025* |
n= number of chemotherapy cycle,
*
p<0.05