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. Author manuscript; available in PMC: 2017 Sep 19.

Published in final edited form as: Int J Legal Med. 2016 Dec 28;131(3):621–628. doi: 10.1007/s00414-016-1516-z

Table 3.

Minor allele frequency of genetic variants in LRRC10 gene

Nucleotide change	MAF (M/m) SUNDS	Control	EAS-CHS^a	EAS^a	EAS^b	SAS^a	SAS^b
Mutations in EAS
c.−2G>T (rs762951776)	0.00568 (175/1)	0.00000 (440/0)	Undetected	Undetected	0.00000 (4028/0)	Undetected	0.00000 (6256/0)
c.385G>A (rs762144273)	0.00442 (225/1)	0.00000 (440/0)	Undetected	Undetected	0.00000 (8640/0)	Undetected	0.00006 (16,481/1)
Rare polymorphism in EAS
c.206C>T (rs140389574)	0.00568 (175/1)	0.00000 (440/0)	0.00000 (210/0)	0.00000 (1008/0)	0.00208 (8630/18)	0.02249 (956/22)	0.01836 (16,197/303)
Common polymorphism in EAS
c.453C>T (rs12229290)	0.00885 (224/2)	0.02045 (431/9)	0.01905 (206/4)	0.02778 (980/28)	0.02953 (8379/255)	0.00000 (978/0)	0.00000 (16,470/0)
Nucleotide change	MAF (M/m) EUR^a		EUR^b	AFR^a	AFR^b	AMR^a	Latino^b
Mutations in EAS
c.−2G>T (rs762951776)	Undetected		0.00003 (35,995/1)	Undetected	0.00000 (5452/0)	Undetected	0.00000 (4998/0)
c.385G>A (rs762144273)	Undetected		0.00000 (73,188/0)	Undetected	0.00000 (10,324/0)	Undetected	0.00000 (11,560/0)
Rare polymorphism in EAS
c.206C>T (rs140389574)	0.00000 (1006/0)		0.00014 (73,176/10)	0.00000 (1322/0)	0.00000 (10,376/0)	0.00000 (694/0)	0.00009 (11,551/1)
Common polymorphism in EAS
c.453C>T (rs12229290)	0.00000 (1006/0)		0.00001 (73,131/1)	0.00000 (1322/0)	0.00000 (10,284/0)	0.00000 (694/0)	0.00017 (11,548/2)

MAF minor allele frequency, M major allele, m minor allele

^a

1000 Genomes Project Phase 3

^b

ExAC