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Effects of charged heterocycle and linear chain on compound activity
| Compd | MIC (µM) | HL50 | CSI | HPLC Rt (min) |
|||
|---|---|---|---|---|---|---|---|
| S. aureus | E. coli |
P. aeruginosa |
K. pneumoniae |
||||
| 3e | 6.2 | >50 | >50 | >50 | 150–300 | 24–48 | 11.276 |
| 4 | 6.2–12.5 | >50 | >50 | >50 | 75–150 | 12–24 | 10.788 |
