Table 5.
Overall tumor information.
| Parameter/variable | N | % | Median (interquartile range) | P-value |
|---|---|---|---|---|
| Tumor detectiona | ||||
| Entire study (N = 389) | 194 | 50 | ||
| First study period (N = 41) | 16 | 39 | ||
| Second study period (N = 92) | 48 | 52 | ||
| Third study period (N = 256) | 130 | 51 | ||
| Location (N = 178) | ||||
| Adrenal | 48 | 27 | ||
| Abdominal/paraspinal | 65 | 36 | ||
| Thoracic/paraspinal | 50 | 28 | ||
| Pelvic | 11 | 6 | ||
| Cervical | 4 | 2 | ||
| Not available | 16 | – | ||
| Type (N = 183) | ||||
| Neuroblastoma | 134 | 73 | ||
| Ganglioneuroblastoma | 41 | 22 | ||
| Ganglioneuroma | 8 | 4 | ||
| Not available | 11 | – | ||
| INSS neuroblastoma stage (N = 118) | ||||
| I | 68 | 58 | ||
| II | 42 | 35 | ||
| III | 6 | 5 | ||
| IV | 2 | 2 | ||
| Not available | 16 | – | ||
| Chemotherapy for tumor (N = 150) | ||||
| Yesb | 20 | 13 | ||
| No | 130 | 87 | ||
| Effect of tumor resection on OMS (N = 134) | ||||
| Improved | 56 | 42 | ||
| Unchanged | 50 | 37 | ||
| Worsened | 28 | 21 | ||
| Age (years) at tumor diagnosis vs tumor type | 0.004*c | |||
| Neuroblastoma | 1.6 (1.2–2.0) | |||
| Other neuroblastic tumors | 1.9 (1.5–2.9) | |||
| Age (years) at neuroblastoma diagnosis vs stage | 0.002*c | |||
| I | 1.5 (1.0–1.7) | |||
| II | 1.7 (1.5–2.4) | |||
| Effect of age (years) at tumor diagnosis vs effect of tumor resection on OMS | ||||
| 0.03c | ||||
| No change/better | 1.7 (1.4–2.3) | |||
| Worse | 1.5 (0.9–2.0) | |||
INSS, International neuroblastoma staging system; OMS, opsoclonus-myoclonus syndrome.
aAll tumors were surgically resected.
bIncludes only patients treated with chemotherapeutic agents for their tumor (adriamycin, cisplatin, cyclophosphamide, dacarbazine, VP16), not for OMS.
cMann–Whitney tests.
*Statistically significant after Bonferroni corrections requiring P < 0.017.