Fig. 3.

Gene set enrichment analysis. The gametocyte-specific genes are to the left of the x-axis, and the asexual-specific genes are to the right. (See main text for a more extensive explanation). Female enrichment score is plotted with a red line, and male enrichment score with a green line. Statistically significant differences (p value < 0.05) are indicated by an asterisk (*). Lines in the “barcode” beneath each plot indicate the position of a gene from that gene set within the ranked list. a Enrichment analysis of two P. berghei datasets. b P. berghei genes were transformed into their P. falciparumsyntenic orthologues, then analysed for enrichment of P. falciparum datasets