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. 2017 Jul 26;14(4):3927–3934. doi: 10.3892/ol.2017.6668

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Copyright: © Glover et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Needle-biopsy specimens immunostained for Bcl-2 and PCNA in serial sections. Left and right panels demonstrate serial section from 2 different prostate needle biopsy specimens. (A) Epithelial cells show weak Bcl-2 staining (left panel) and heavy cytoplasmic staining for Bcl-2 (right panel). (B) Needle-biopsy specimens immunostained for PCNA within the serial sections of the same specimen. Intense PCNA in cells which do not express Bcl-2 (left panel) whereas little-to-no expression of PCNA is observed in cells expressing Bcl-2 (right panel). Arrows showing cells expressing high PCNA but not Bcl-2, and vice versa. PCNA, proliferating cell nuclear antigen.