Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A hypothetical model showing how chronic inflammation leads to cancer development. Under the influence of chronic inflammation epithelial cells acquire increased survival with an increase in Bcl-2 expression. The survival signal alters the phenotype of these particular epithelial cells, which gain neoplastic characteristics, leading to precursors that may later acquire increased proliferation rate leading to cancer development and subsequent progression.
