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Caspase-3 activity after irradiation. After 5-Gy irradiation, the parent (TE4) cells and RRCs (MT-CO1-downregulated cells) were incubated with colorimetric substrate DEVD-pNA for 24 h. Caspase-3 activity was measured as the absorbance at 405 nm and was found to be higher in parent cells after irradiation (*P<0.001). Error bars represent the standard deviation of the mean. MT-CO1, cytochrome c oxidase 1; RRCs, radioresistant cells.
