Figure 2.
Effect of treatment with 5-aza-CdR on promoter methylation status and BTG1 expression in ovarian cancer cell lines. (A) Reduction in methylation of the BTG1 gene promoter region by treatment with 5-aza-CdR. (B) Restoration of BTG1 mRNA expression by treatment with 5-aza-CdR. ***P < 0.001 versus pretreatment. (C) Western blot for BTG1 before and after demethylation.