Fig. 3.
Representative electron micrographs of gonadotrophs in normal and female mutant mice: (a) C57 Normal, (b) FSHβKO, (c) FSHRKO, (d) LuRKO, (e) hpg and (f) ovariectomised (OVX). Scale bar = 2 µm. Representative organelles are labelled: m, mitochondria; rer, rough endoplasmic reticulum; sg secretory granule; n, nucleus; g, Golgi apparatus. (D) Arrowheads indicate granules at the periphery of the gonadotroph. FSH, follicle-stimulating hormone; hpg, hypogonadal; KO, knockout; LuR, luteinising hormone receptor; R, receptor.