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. Author manuscript; available in PMC: 2017 Sep 19.
Published in final edited form as: Chem Commun (Camb). 2013 May 14;49(50):5621–5629. doi: 10.1039/c3cc42236d

Scheme 5.

Scheme 5

(A) Radiosynthesis of [11C]CURB; (B) Mechanism of FAAH radiolabelling with [11C]CURB; the radiolabel must be placed on the carbonyl or N-alkyl fragment of the tracer to effectively measure levels of FAAH in the brain. Asterisk denotes 11C.