Table 2.
Odds Ratios of Neuropathology Outcomes for Predicted HDL and Non-HDL Levels at Age 70
| Outcome | Freq (N) | Odds Ratio (95% CI) for a 1 SD Difference
|
|
|---|---|---|---|
| HDL | Non-HDL | ||
| Braak Stage 5 or 6 | 89 (314) | 0.97 (0.74, 1.28) | 1.04 (0.80, 1.35) |
| CERAD Intermediate or Frequent | 149 (314) | 0.83 (0.65, 1.06) | 0.99 (0.78, 1.24) |
| Any Cerebral Amyloid Angiopathy | 92 (312) | 1.20 (0.92, 1.56) | 1.02 (0.79, 1.31) |
|
| |||
| Presence of Cystic Infarcts | 97 (311) | 0.90 (0.69, 1.17) | 1.13 (0.89, 1.43) |
| Presence of Microinfarcts | |||
| Any | 106 (313) | 0.86 (0.66, 1.12) | 1.00 (0.79,1.28) |
| Any cerebral | 35 (313) | 1.04 (0.80, 1.34) | 1.03 (0.81, 1.30) |
| Any deep | 97 (311) | 0.81 (0.61, 1.06) | 1.02 (0.79, 1.31) |
|
| |||
| Lewy Body Disease | |||
| Any | 54 (314) | 1.00 (0.72, 1.39) | 1.35 (1.02, 1.79)* |
| SN or LC | 42 (314) | 0.73 (0.50, 1.09) | 1.45 (1.07, 1.96)* |
| Amygdala | 53 (299) | 1.18 (0.83, 1.69) | 1.29 (0.95, 1.74) |
| Frontal or temporal cortex | 18 (313) | 1.10 (0.65, 1.86) | 1.45 (0.99, 2.13) |
p<.05