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. Author manuscript; available in PMC: 2017 Sep 19.
Published in final edited form as: Cell Signal. 2014 Dec 11;27(3):453–459. doi: 10.1016/j.cellsig.2014.11.037

Fig. 5.

Fig. 5

Defective Rac1, RhoA and cdc42 activity in Tgfbr3−/− epicardial cells. (A–B) Detection of GTP-Rac1 in Tgfbr3+/+ and Tgfbr3−/− epicardial cells incubated with 300 μg/mL HMWHA for 15 min. (C–D) Detection of GTP-Rac1 in Tgfbr3+/+ and Tgfbr3−/− epicardial cells incubated with 300 μg/mL HMWHA for 5 and 15 min. (E–F) Detection of GTP-cdc42 in Tgfbr3+/+ and Tgfbr3−/− epicardial cells incubated with 300 μg/mL HMWHA for 15 min. (G) Phase contrast microscopy visualizing filopodia of Tgfbr3+/+ and Tgfbr3−/− epicardial cells. (H) Quantification of filopodia in Tgfbr3+/+ and Tgfbr3−/− epicardial cells (*p = 5.90973E–08).