Table 2.
Lice-free dogs and households after a single oral administration of fluralaner or topical administration of permethrin to dogs naturally infested with lice L. setosus
| Study day | Lice-free dogs | Lice-free households | ||||||
|---|---|---|---|---|---|---|---|---|
| Fluralaner (%) | Permethrin (%) | Lower 97.5% CLa | P-valueb | Fluralaner (%) | Permethrin (%) | Lower 97.5% CLa | P-valueb | |
| 1 | 64 | 20.0 | 0.0417 | 0.0019 | 62 | 13 | 0.0554 | 0.0020 |
| 7 | 79 | 44.4 | -0.0502 | 0.0070 | 77 | 43 | -0.0858 | 0.0121 |
| 28 | 100 | 87.5 | -0.1311 | 0.0177 | 100 | 83 | -0.1182 | 0.0147 |
| 84 | 100 | na | – | – | 100 | na | – | – |
Abbreviation: na not applicable
aConfidence limits based upon the Farrington-Manning test of non-inferiority for the risk difference. Results > -0.15 for significant non-inferiority and results > 0 for significant one-sided superiority with α = 0.025
bFarrington-Manning test of non-inferiority for the risk difference