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. 2017 Sep 18;19:208. doi: 10.1186/s13075-017-1410-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Change from baseline over time in the Physical Component Score (PCS) (a) and Mental Component Score (MCS) (b) of the Short Form-36 (SF-36). The dashed line represents the minimum clinically important difference (MCID) in the SF-36 PCS (≥ 5 points) and SF-36 MCS (≥ 5 points). MTX methotrexate