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. 2017 Sep 18;19:209. doi: 10.1186/s13075-017-1384-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Gene expression of matrix macromolecules (aggrecan and collagen II) and glycosaminoglycan (GAG) content from nucleus pulposus (NP) cells in scaffold culture. 20% deformation compression significantly downregulated gene expression of matrix molecules (a) and decreased GAG content (b), which could be partly reversed by treatment with the ROS scavenger NAC. Data are expressed as the mean ± SD (n = 3). *Indicates a significant difference (p < 0.05) between two groups; #indicates a significant difference (p < 0.05) compared with the control group