Table 1.
qPCR Panel of Immune Genesa
| PS | PS coat | |
|---|---|---|
| CD4(***) | 1.132σ ± 0.18 | 0.6169σ ± 0.15 |
| IL-10(n.s) | 1σ ± 0.17 | 0.9265σ ± 0.11 |
| TLR9(*) | 1.561σ ± 0.18 | 1σ ± 0.18 |
| MyD88(***) | 1.569σ ± 0.12 | 1σ ± 0.13 |
| TLR2(***) | 1.757σ ± 0.15 | 0.9908σ ± 0.18 |
| TNF-a(**) | 1.635σ ± 0.19 | 1.089σ ± 0.19 |
a
RAW macrophages were stimulated for 4 h with PS or PS coat particles at 1:1 stoichiometry of particles to cells and then assayed. Values shown are fold change over unstimulated cells. Red, grey, and green signify upregulation, no change, and down regulation, respectively. Statistical significance between PS and PS coat values: CD4 (***); IL-10 (n.s.); TLR9 (*); MyD88 (***); TLR2 (***); TNF-α (**).
*
p < 0.05,
**
p < 0.01,
***
p < 0.001.