Table 1.
Correlation of clinicopathological parameters with Foxp3 and VEGF-C in cervical cancer patients
| Clinical parameter | Foxp3 expression | P value | VEGF-C expression | P value | ||
|---|---|---|---|---|---|---|
| Positive (%) | Negative (%) | Positive (%) | Negative(%) | |||
| Age (year) | ||||||
| < 50 | 14 (28) | 10 (20) | 20 (40) | 4 (8) | ||
| ≥ 50 | 19 (38) | 7 (14) | 0.373 | 18 (36) | 8(16) | 0.327 |
| Differentiation | ||||||
| High + moderate | 17(34) | 8 (16) | 23 (46) | 4 (8) | ||
| Low | 16(32) | 9 (18) | 1.000 | 15 (30) | 8(16) | 0.183 |
| Tumor size | ||||||
| < 4 cm | 12 (24) | 9 (18) | 16 (32) | 5 (10) | ||
| ≥ 4 cm | 21 (42) | 8 (16) | 0.366 | 22 (44) | 7 (14) | 0.624 |
| Histological type | ||||||
| Squamous carcinoma | 30 (60) | 12 (24) | 34 (68) | 8(16) | ||
| Adenocarcinoma | 3 (6) | 5 (10) | 0.102 | 4 (8) | 4 (8) | 0.082 |
| Clinical stage | ||||||
| I + II | 19(38) | 16 (32) | 30(60) | 5(10) | ||
| III + IV | 14(28) | 1(2) | 0.009 | 8 (16) | 7 (14) | 0.027 |
| Lymph node metastasis | ||||||
| Absent | 19(38) | 15(30) | 23 (46) | 11(22) | ||
| Present | 14(28) | 2(4) | 0.026 | 15 (30) | 1 (2) | 0.042 |