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. 2017 Apr 1;9(4):843–854. doi: 10.1093/gbe/evx035

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© The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 2.— — Compensatory changes in regulation are common between species. (A) Number of genes within each regulatory divergence category versus sequence divergence. Genes were classified into one of five categories based on statistical support: Black, conserved. Red, cis-regulatory difference only. Orange, compensatory. Blue, trans-regulatory difference only. Purple, reinforcing. (B) Median absolute magnitude of effect for the cis-regulatory (top) and trans-regulatory (bottom) components of genes with a compensatory mode of regulatory divergence (orange) or reinforcing mode of regulatory divergence (purple) versus sequence divergence. Error bars are 99% CI from bootstrap analysis.