Table 2.

HR of death in patients with AAV across subgroups identified by multivariable Cox regression

	HR	LCL HR	UCL HR	p Value
Female	1			(reference)
Male (0–1.85 years)	2.04	0.99	4.20	0.053
Male (1.85–8.5 years)	0.90	0.49	1.67	0.747
Male (>8.5 years)	0.35	0.13	0.94	0.036
Age (1-year increase)	1.09	1.07	1.12	<0.001
Diagnosis GPA	1			(reference)
Diagnosis EGPA	0.60	0.09	4.14	0.606
Diagnosis MPA	1.40	0.80	2.44	0.234
ANCA PR3	1			(reference)
ANCA MPO	0.94	0.57	1.54	0.807
ANCA negative	2.24	0.46	11.00	0.320
CKD 1–2	1			(reference)
CKD 3	1.14	0.56	2.36	0.713
CKD 4	1.75	0.89	3.45	0.108
CKD 5	2.51	1.30	4.83	0.006

AAV, ANCA-associated vasculitides; ANCA, antineutrophil cytoplasmatic antibodies; CKD, chronic kidney disease; EGPA, eosinophilic granulomatosis with polyangiitis; GPA, granulomatosis with polyangiitis; LCL, lower confidence limit; MPA, microscopic granulomatosis; MPO, myeloperoxidase; PR3, proteinase 3; UCL; upper confidence limit.