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. 2017 Sep 14;2(4):e000208. doi: 10.1136/esmoopen-2017-000208

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© European Society for Medical Oncology (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Histological and molecular heterogeneity of triple negative breast cancer (TNBC). (A) Most TNBCs are infiltrating ductal carcinoma (IDC), leading to bad prognosis. The other types of TNBCs have better prognosis, with the exception of metaplastic and inflammatory. (B) There is a high overlap between TNBC and basal-like breast cancer, however, not all TNBCs are basal-like and vice versa. (C) Some patients with TNBC have a BRCA1 germline mutation, which leads to an improved patient prognosis.