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. Author manuscript; available in PMC: 2018 Oct 30.
Published in final edited form as: Psychiatry Res. 2017 Aug 19;268:22–26. doi: 10.1016/j.pscychresns.2017.08.006

Figure 1.

Figure 1

This Cox regression survival analysis of age at onset of substance use disorder (SUD) shows the influence of OFC/amygdala ratios on SUD outcome. The analysis included whether the individual was in a group with the OFC/amygdala ratio below or above the median of the sample, adjusted for risk group membership and age at scan. Individuals with volume ratios of the orbitofrontal cortex (OFC) to amygdala below the median had significantly earlier ages of substance use disorder onset than those with ratios above the median.