Table 2.

Cost-effectiveness of CTC as compared with no screening and colonoscopy.

Author, year*	CTC specificity	CTC/colonoscopy cost ratio	CTC cost-effective as compared with no screening	CTC cost-effective as compared with colonoscopy	If not cost-effective vs colonoscopy, CTC may reverse when varying
Sonnenberg et al., 1999	95%	0.65	Yes	No	Cost/adherence
Ladabaum et al., 2004	85%	1	Yes	No	Cost
Heitman et al., 2005	84%	0.8	NA	No	Cost/adherence/CTC accuracy/natural history
Vijan et al., 2007	91%	0.8	Yes	No	Accuracy/cost
Hassan et al., 2008	86%	0.8	Yes	Yes	-
Lee et al., 2010	88%	0.3	NA	No	NA
Knudsen et al., 2010**	80%–88%	1	Yes	No	Cost/adherence
Heresbach et al., 2010	NA	NA	Yes	NA	NA

^*In the case of multiple publications, the most recent was included.

^§Without further classification.

^**MISCAN model