Figure 4.

(A) Baseline percent collagen deposition by immune responder status. Plus signs denote the median. (B) Percent change in collagen deposition in the lamina propia (LP) at week 22. (C) Baseline collagen synthesis rates (percent new per week) of guanidine-soluble and guanidine-insoluble collagen in all participants measured by heavy water labeling. (D) Change in collagen synthesis rates (percent new per week) of guanidine-soluble collagen in the placebo and lisinopril groups at baseline and at week 22.