Skip to main content
. Author manuscript; available in PMC: 2017 Sep 19.
Published in final edited form as: J Mol Eng Mater. 2016 Aug 22;4(1):1640005. doi: 10.1142/S2251237316400050

Table 1.

Physical chemical properties and amino acid sequences for TiBP, AMP, and two chimeric peptides TiBP-Spacer3-AMP and TiBP-Spacer5-AMP.

Name Sequence Spacer length MW (kDa) PI Charge GRAVY
TiBP RPRENRGRERGL N/A 1.4956 11.82 +3 −2.633
AMP LKLLKKLLKLLKKL N/A 1.6923 10.70 +6 0.500
TiBP-Spacer 3-AMP RPRENRGRERGL −GGG LKLLKKLLKLLKKL 3 3.3411 11.85 +9 −0.890
TiBP-Spacer 5-AMP RPRENRGRERGL GSGGG LKLLKKLLKLLKKL 5 3.4852 11.85 +9 −0.871

Notes: MW, molecular weight; pI, isoelectric point; GRAVY, GRand Average Value of hydropathicitY; and “−”, gap inserted for sequence alignment. Despite chimeric peptide similarity to one another, we observed improved antimicrobial activity with the altered amino acid composition of the longer peptide spacer, Spacer5.