Skip to main content
. 2017 Sep 19;12(9):e0184777. doi: 10.1371/journal.pone.0184777

Table 7. MA intralesional therapy schedules among Old World leishmaniasis studies.

Year, (Author) Country (cases) Number of infiltrations Interval between infiltrations (days) Treatment duration (interval between the first and the last infiltration in days)
2016, Jaffary Iran Mean 13.6 2 (twice a week) Maximum 32
2016, Rajabi Iran 8 7 56
2016, Yesilova Turkey 8 2 (twice a week) 28
2015, Ranawaka Sri Lanka 3.7 7 days between the first 3 injections; 14 days between the fourth and fifth injections; then every 30 days until cure Up to 109
2015, Refai Sri Lanka Up to 10 7 Up to70
2014, Stahl Afghanistan NR daily treatments (with the exception of Fridays) during the first week, twice a week until the end of week 4and thereafter once a week until wound closure 28
2014, Agrawal Iran 5 to 7 2 (twice a week) or 7 NR
2014, Solomon Israel Mean 3 every 21 to 28 NR
2014, Niforoushzadeh Iran Up to 8 2 (twice a week) 28
2013, Mohammadzadeh Iran 6 to 15 2 (twice a week) Up to 56
2013, Bumb India 7 2 (twice a week) 28
2012, Maleki Iran 6 7 42
2012, Niforoushzadeh Iran Up to 16 2 (twice a week) 56
2012, Safi Afghanistan 5 7 35
2011, Layegh Iran Up to 8 7 56
2010, van Thiel Afghanistan Median 5 1 at 3 Up to 56
2010, Bumb India 5 to 7 7 49
2010, Ranawaka Sri Lanka NR 7 days between the first 3 injections; 14 days between the fourth and fifth injections; then every 30 days until cure NR
2009, Solomon Israel mean 2,5 every 21 to 28 Mean 53
2009, Layegh Iran Mean 4 NR 42
2008, Qasmi Morocco 3 to5 7 Up to 35
2007, Nilforoushzadeh Iran Up to 6 7 Up to 42
2007, Sadeghian Iran 4 7 28
2006, Nilforoushzadeh Iran Up to 6 7 42
2006, Salmanpour Iran 6 to 8 7 42 to56
2006, Sadeghian Iran 6 to 10 7 42 to70
2005, Shazad Iran 10 1 20
2003, Niforoushzadeh Iran 6 7 42
2003, Faghihi Iran Up to 12 7 Up to 90
2001, Salmanpour Iran 6 to 8 15 120
1999, Chahed Tunisia NR 2 (twice a week) NR
1990, el Darouti Arab Emirates 10 1 20
1979, Ghosn Syria Mean 3.4 7 Up to 28

NR: no reported