Table 7. MA intralesional therapy schedules among Old World leishmaniasis studies.
Year, (Author) | Country (cases) | Number of infiltrations | Interval between infiltrations (days) | Treatment duration (interval between the first and the last infiltration in days) |
2016, Jaffary | Iran | Mean 13.6 | 2 (twice a week) | Maximum 32 |
2016, Rajabi | Iran | 8 | 7 | 56 |
2016, Yesilova | Turkey | 8 | 2 (twice a week) | 28 |
2015, Ranawaka | Sri Lanka | 3.7 | 7 days between the first 3 injections; 14 days between the fourth and fifth injections; then every 30 days until cure | Up to 109 |
2015, Refai | Sri Lanka | Up to 10 | 7 | Up to70 |
2014, Stahl | Afghanistan | NR | daily treatments (with the exception of Fridays) during the first week, twice a week until the end of week 4and thereafter once a week until wound closure | 28 |
2014, Agrawal | Iran | 5 to 7 | 2 (twice a week) or 7 | NR |
2014, Solomon | Israel | Mean 3 | every 21 to 28 | NR |
2014, Niforoushzadeh | Iran | Up to 8 | 2 (twice a week) | 28 |
2013, Mohammadzadeh | Iran | 6 to 15 | 2 (twice a week) | Up to 56 |
2013, Bumb | India | 7 | 2 (twice a week) | 28 |
2012, Maleki | Iran | 6 | 7 | 42 |
2012, Niforoushzadeh | Iran | Up to 16 | 2 (twice a week) | 56 |
2012, Safi | Afghanistan | 5 | 7 | 35 |
2011, Layegh | Iran | Up to 8 | 7 | 56 |
2010, van Thiel | Afghanistan | Median 5 | 1 at 3 | Up to 56 |
2010, Bumb | India | 5 to 7 | 7 | 49 |
2010, Ranawaka | Sri Lanka | NR | 7 days between the first 3 injections; 14 days between the fourth and fifth injections; then every 30 days until cure | NR |
2009, Solomon | Israel | mean 2,5 | every 21 to 28 | Mean 53 |
2009, Layegh | Iran | Mean 4 | NR | 42 |
2008, Qasmi | Morocco | 3 to5 | 7 | Up to 35 |
2007, Nilforoushzadeh | Iran | Up to 6 | 7 | Up to 42 |
2007, Sadeghian | Iran | 4 | 7 | 28 |
2006, Nilforoushzadeh | Iran | Up to 6 | 7 | 42 |
2006, Salmanpour | Iran | 6 to 8 | 7 | 42 to56 |
2006, Sadeghian | Iran | 6 to 10 | 7 | 42 to70 |
2005, Shazad | Iran | 10 | 1 | 20 |
2003, Niforoushzadeh | Iran | 6 | 7 | 42 |
2003, Faghihi | Iran | Up to 12 | 7 | Up to 90 |
2001, Salmanpour | Iran | 6 to 8 | 15 | 120 |
1999, Chahed | Tunisia | NR | 2 (twice a week) | NR |
1990, el Darouti | Arab Emirates | 10 | 1 | 20 |
1979, Ghosn | Syria | Mean 3.4 | 7 | Up to 28 |
NR: no reported