Table 1. Blood values in mice treated with vehicle or finerenone.
ref. values [22] | vehicle | finerenone 1 mg/kg/d |
P value | finerenone 10 mg/kg/d |
P value | |
---|---|---|---|---|---|---|
Potassium [mmol/l] | 3.1–6.1 | 5.1±0 | 4.33±0.16 | n.s. | 4.6±0.2 | n.s. |
Sodium [mmol/l] | 149–165 | 163±2 | 163.00±2.00 | n.s. | 164±0.00 | n.s. |
Chlorid [mmol/l] | n/a | 104±2 | 107.33±1.11 | n.s. | 102±3 | n.s. |
creatinine [μmol/l] | 28–11 | 8.5±2.5 | 6.67±0.44 | n.s. | 12±0.00 | n.s. |
Urea [mmol/l] | 3.2–13.2 | 11.4±0.7 | 11.871.42 | n.s. | 10.65±0.65 | n.s. |