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. 2017 Sep 19;12(9):e0184888. doi: 10.1371/journal.pone.0184888

Table 1. Blood values in mice treated with vehicle or finerenone.

ref. values [22] vehicle finerenone
1 mg/kg/d
P value finerenone
10 mg/kg/d
P value
Potassium [mmol/l] 3.1–6.1 5.1±0 4.33±0.16 n.s. 4.6±0.2 n.s.
Sodium [mmol/l] 149–165 163±2 163.00±2.00 n.s. 164±0.00 n.s.
Chlorid [mmol/l] n/a 104±2 107.33±1.11 n.s. 102±3 n.s.
creatinine [μmol/l] 28–11 8.5±2.5 6.67±0.44 n.s. 12±0.00 n.s.
Urea [mmol/l] 3.2–13.2 11.4±0.7 11.871.42 n.s. 10.65±0.65 n.s.