Table 1.
Patient, disease and treatment characteristics for both groups
| Characteristic | Group <70, N (%) | Group ≥70, N (%) | p-value |
|---|---|---|---|
| Age (years) | |||
| ≤55 | 37 (46.8) | 61 (59.8) | χ2 (1) = 3.0 |
| >55 | 42 (53.2) | 41 (40.2) | p = 0.082 |
| Gender | |||
| Male | 69 (87.3) | 79 (77.5) | χ2 (1) = 2.9 |
| Female | 10 (12.7) | 23 (22.5) | p = 0.087 |
| Site | |||
| Larynx | 15 (19.0) | 9 (8.8) | n.a. |
| Oral cavity | 8 (10.1) | 7 (6.9) | |
| Oropharynx | 22 (27.8) | 30 (29.4) | |
| Nasopharynx | 14 (17.7) | 31 (30.4) | |
| Pharyngeal–laryngeal | 11 (13.9) | 15 (14.7) | |
| Hypopharynx | 7 (8.9) | 8 (7.8) | |
| Others | 2 (2.5) | 2 (2.0) | |
| T stage | |||
| 1–2 | 40 (50.6) | 49 (48.0) | χ2 (1) = 0.1 |
| 3–4 | 39 (49.4) | 53 (52.0) | p = 0.715 |
| N stage | |||
| 0–1 | 30 (38.0) | 21 (20.6) | χ2 (1) = 7.5 |
| 2–3 | 49 (62.0) | 81 (79.4) | p = 0.006 |
| Type of RTCT | |||
| Concomitant CT | 53 (67.1) | 71 (69.6) | χ2 (2) = 0.1 |
| Sequential CT | 11 (13.9) | 13 (12.7) | p = 0.936 |
| Intensive RTa | 15 (19.0) | 18 (17.6) | |
| RT techniqueb | |||
| 3DCRT | 3 (3.8) | 4 (3.9) | Fisher = 53.1 |
| fIMRT | 34 (43.0) | 2 (2.0) | p < 0.001 |
| rIMRT | 29 (36.7) | 56 (54.9) | |
| IMRT | 13 (16.5) | 40 (39.2) | |
| Total | 79 | 102 | |
3DCRT, three-dimensional conformal radiotherapy; fIMRT, forwardly optimized intensity-modulated radiation therapy; IMRT, intensity-modulated radiation therapy; RTCT radiochemotherapy; rIMRT, rapid intensity-modulated radiation therapy; RT, radiation therapy.
a
In intensive RT, RT was used as the single oncological treatment.
b
fIMRT uses sequential plans manually optimized, rIMRT and IMRT are inversely optimized IMRT with simultaneous integrated boost using a different number of segments (approximately 35 and 75, respectively).