Table 2.
Baseline demographic and pathological tumour characteristics of the 163 patients with primary pancreatic ductal adenocarcinoma
| Variable | DPC4-expression (n = 75) | DPC4-non-expression (n = 88) | p-value |
|---|---|---|---|
| Age (years) | 61.9 ± 9.5 | 61.8 ± 9.1 | 0.941 |
| Sex (M : F) | 43 : 32 | 49 : 39 | 0.832 |
| Tumour location | |||
| Head | 48 (64.0%) | 64 (72.7%) | 0.231 |
| Body/tail | 27 (36.0%) | 24 (27.3%) | |
| Initial presentation | |||
| Symptomatica | 48 (64.0%)a | 63 (71.6%)a | 0.300 |
| Incidental | 27 (36.0%) | 25 (28.4%) | |
| Type of operation | |||
| Total pancreatectomy | 11 (14.7%) | 13 (14.8%) | 0.985 |
| Pancreaticoduodenectomy | 46 (61.3%) | 51 (58.0%) | 0.661 |
| Distal pancreatectomy | 18 (24.0%) | 24 (27.3%) | 0.634 |
| Tumour grade | |||
| Grade 1 | 11 (14.7%) | 9 (10.2%) | 0.569 |
| Grade 2 | 50 (66.7%) | 65 (73.9%) | |
| Grade 3 | 14 (18.7%) | 14 (15.9%) | |
| T stage | |||
| T1 | 5 (6.7%) | 3 (3.4%) | 0.179 |
| T2 | 4 (5.3%) | 1 (1.1%) | |
| T3 | 66 (88.0%) | 84 (95.5%) | |
| Tumour stage (TNM) | |||
| I | 8 (10.7%) | 3 (3.4%) | 0.066 |
| II | 67 (89.3%) | 85 (96.6%) | |
| Residual tumour | |||
| R0 | 67 (89.3%) | 75 (85.2%) | 0.435 |
| R1 | 8 (10.7%) | 13 (14.8%) | |
| R2 | 0 (0.0%) | 0 (0.0%) | |
F, female; M, male.
Data are represented as mean ± standard deviation or number (percentage).
a
111 patients with initial symptoms, including 74 patients with pain, 30 patients with jaundice, 5 patients with indigestion and 2 patients with nausea and vomiting.