Table 2.
Patient characteristics in population of patients who experienced fractures
Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age | 57 | 73 | 68 | 64 | 69 | 87 | 75 | 76 | 65 | 62 | 67 | 63 | 86 | 66 | 55 |
Site of PIF | Cervical cancer | Cervical cancer | Cervical cancer | Cervical cancer | Cervical cancer | Cervical cancer | Endometrial cancer | Endometrial cancer | Endometrial cancer | Endometrial cancer | Anal canal | Anal canal | Anal canal | Anal canal | Anal canal |
Histology of the primary tumour | SCC | SCC | SCC | SCC | SCC | SCC | ADK | ADK | ADK | ADK | SCC | SCC | SCC | SCC | SCC |
Stage/FIGO/ | IIIb | IV | IIb | III | IIb | II | II | IIIc | Ib | II | II | IIIa | IIIa | IIIb | IIIa |
Latency period (months) | 34 | 66 | 11 | 3 | 3 | 7 | 11 | 13 | 15 | 16 | 10 | 36 | 46 | 6 | 8 |
RT treatment modalities volume dose (Gy) |
IMRT pelvis + LA : 45 Gy boost to T and pelvic LN 20 Gy (TD 65 Gy) |
IMRT pelvis + LA: 45 Gy |
IMRT pelvis + LA : 45 pelvic LN :57.6 brachytherapy 25 Gy PDR |
IMRT pelvis 45 LN:59 T: 65 Gy |
Pre-operative PDR brachytherapy 60 Gy IMRT pelvis 45 N 50 Gy |
IMRT pelvis 45 T 65 Gy |
IMRT pelvis 45 + curie 10 Gy HDR |
IMRT pelvis 45 T 50 |
IMRT pelvis 45 + brachytherapy 10 Gy HDR |
IMRT pelvis 45 T 50.4 brachytherapy 15 Gy PDR |
IMRT pelvis 45 T 65 |
IMRT pelvis 45 T 65 LN 51 |
IMRT pelvis 45 T 65 |
IMRT pelvis 45 T 65 |
IMRT pelvis 45 T 65 |
Maximal dose at the site of the PIF (Gy) | 68.4 | 47.3 | 58.5 | 57.1 | 50.3 | 58.3 | 45.5 | 40.8 | 45.5 | 45.2 | 52.6 | 48.8 | 46.4 | 62.3 | 65.1 |
ADK, adenocarcinoma; FIGO, International Federation of Gynecology and Obstetrics; HDR, high dose rate; IMRT, intensity-modulated radiation therapy; LA, lomboaortic; LN, lymph node; PDR, pulse dose rate; PIF, pelvic insufficiency fracture; SCC, squamous-cell carcinoma; T, tumour; TD, total dose.