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. Author manuscript; available in PMC: 2017 Sep 19.
Published in final edited form as: J Med Chem. 2017 Jul 11;60(14):6191–6204. doi: 10.1021/acs.jmedchem.7b00435

Figure 7.

Figure 7

Inactive compound 8f does not decrease ER stress related mRNA levels induced by Tm. INS-1 cells were treated with or without Tm (0.1 µg/mL) in the presence of 8f or DMSO for 8 h. ATF4 (A), CHOP (B), Bip (C), GRP94 (D), and XBP1s (E) mRNA levels were analyzed by qRT-PCR. Relative mRNA levels were normalized against the housekeeping gene Cyclophilin A using the comparative CT method. The results are the means of 3 replicate wells and representative of 3 independent experiments. Error bars indicate SD.