Table 3.
Chemoradiotherapy-induced toxicity in the propensity-matched VMAT and ssIMRT cohorts
| Events | VMAT Group (n = 65) |
ssIMRT Group (n = 130) |
P Value | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of events (%) | Toxicity |
Grade |
No. of events (%) | Toxicity |
Grade |
||||||||
| 1 | 2 | 3 | 4 | 5 | 1 | 2 | 3 | 4 | 5 | ||||
| Radiation pneumonitis | 6 (9.2) | 2 | 4 | 0 | 0 | 0 | 20 (15.4) | 10 | 6 | 1 | 1 | 2 | .233 |
| Pulmonary fibrosis | 0 | 0 | 0 | 0 | 0 | 0 | 7 (5.4) | 7 | 0 | 0 | 0 | 0 | .057 |
| Pleural effusion | 5 (7.7) | 4 | 1 | 0 | 0 | 0 | 20 (15.4) | 18 | 1 | 1 | 0 | 0 | .057 |
| Arrhythmia | 1 (1.5) | 1 | 0 | 0 | 0 | 0 | 2 (1.5) | 0 | 1 | 1 | 0 | 0 | 1.000 |
| Pericardial effusion | 1 (1.5) | 0 | 1 | 0 | 0 | 0 | 9 (6.9) | 0 | 8 | 1 | 0 | 0 | .108 |
| Esophagitis | 57 (87.7) | 16 | 33 | 8 | 0 | 0 | 73 (56.1) | 12 | 44 | 17 | 0 | 0 | 0 |
| Fistula | 1 (1.5) | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .156 |
| Esophageal stricture | 8 (12.3) | 3 | 2 | 3 | 0 | 0 | 13 (10.0) | 1 | 4 | 8 | 0 | 0 | .624 |
| Feeding tube | 15 (23.1) | 32 (24.6) | .813 | ||||||||||
ssIMRT, step and shoot intensity-modulated radiotherapy; VMAT, volumetric modulated arc therapy.