Table 2.
Select baseline patient, disease and treatment characteristics between cohortsa
| Characteristic | Trimodality | Unplanned Bimodality | Planned Bimodality | P-value |
|---|---|---|---|---|
| Age | ||||
| Median/range | 56/38-79 | 58/39-86 | 64/30-83 | < .001 |
| <60 | 52 (59.1) | 47 (54) | 68 (38.2) | |
| ≥60 | 36 (40.9) | 40 (46) | 110 (61.8) | |
| Sex | ||||
| Male | 50 (56.8) | 46 (51.7) | 107 (52.7) | .422 |
| Female | 38 (43.2) | 43 (48.3) | 71 (46.7) | |
| Race | ||||
| Black | 23 (26.1) | 33 (37.1) | 94 (52.8) | < .001 |
| Non-Black | 65 (73.9) | 56 (62.9) | 84 (47.2) | |
| ECOG Performance Status | ||||
| 0 | 63 (72.4) | 47 (53.4) | 55 (33.3) | < .001 |
| ≥1 | 24 (27.6) | 41 (46.6) | 121 (65.1) | |
| Smoking (pack-years) | ||||
| Median/range | 34/0-180 | 38/0-150 | 45/0-212 | .044 |
| COPD diagnosis | ||||
| Yes | 13 (14.9) | 22 (25.3) | 65 (36.9) | .001 |
| Charlson Comorbidity Status | ||||
| <6 | 60 (68.2) | 59 (55.7) | 80 (44.9) | .001 |
| ≥6 | 28 (31.8) | 39 (44.3) | 98 (55.1) | |
| Marital Status | ||||
| Married | 59 (67) | 53 (59.6) | 73 (41) | < .001 |
| Non-married | 29 (33) | 36 (40.4) | 105 (59) | |
| Median Household Income | ||||
| ≥43,723 | 56 (65.1) | 44 (51.8) | 72 (40.4) | .001 |
| Overall Stage | ||||
| IIIA | 66 (75) | 54 (60.7) | 80 (44.9) | < .001 |
| IIIB | 22 (25) | 35 (39.3) | 98 (55.1) | |
| T-stage | ||||
| TX | 0 (0) | 4 (4.5) | 14 (7.9) | .044 |
| ≤T2 | 48 (54.5) | 39 (44.3) | 74 (41.8) | |
| ≥T3 | 40 (45.5) | 45 (51.1) | 89 (50.3) | |
| N-stage | ||||
| NX | 1 (1.1) | 1 (1.1) | 1 (0.6) | .039 |
| ≤N1 | 14 (15.9) | 11 (12.5) | 31 (17.5) | |
| N2 | 64 (72.7) | 58 (65.9) | 96 (54.2) | |
| N3 | 9 (10.2) | 18 (20.5) | 49 (27.7) | |
| N2-stage | ||||
| Single station | 36 (56.3) | 25 (43.1) | 35 (36.5) | .128 |
| Multi-nodal | 22 (34.4) | 27 (46.6) | 53 (55.2) | |
| Unknown | 6 (9.4) | 6 (10.3) | 8 (8.3) | |
| Radiation Dose Delivered (Gy) | ||||
| Median/range | 61.2/39.6-69.6 | 66/10-70.2 | 63/19.8-81.6 | .108 |
| ≥60 Gy | 79 (93) | 73 (85.8) | 141 (81) | .040 |
| Adjuvant Chemotherapy | ||||
| Yes | 65 (80.2) | 54 (70.1) | 93 (63.7) | .034 |
COPD, chronic obstructive pulmonary disease; ECOG, Eastern Cooperative Oncology Group.
a
The number of patients in each cohort (%).