Pro-inflammatory cytokines analyzed in serum samples from lean and HFD fed mice with and without IRI, demonstrated significantly increased levels in HFD IRI+ Graphical representation of levels of (A) IL-6, (B) IL-1β, (C) keratinocyte-derived chemoattractant, (D) IL-2, (E) IP-10, and (F) MIG are shown. Data represents mean ± SEM of at least 10 mice in each group of 3 independent experiments. Asterisks indicates p<0.05, Two-way Anova).