Table 1.
Characteristics and demographic data of ovarian cancer cell lines
| Cell line | Age | Race | FIGO* stage | Primary site | Histology | Flow cytometry (MFI)** | FISH*** | Flow cytometry IHC score cell block | IHC Tissue block |
|---|---|---|---|---|---|---|---|---|---|
| KRCH31**** | 69 | W | IV | Ovary | Serous | 119.68 | Amplified | 3+ | 3+ |
| OVA11 | 79 | W | IC | Ovary | Clear cell | 290.76 | Amplified | 3+ | 1+ |
| OVA10 | 51 | W | IIC | Ovary | Clear cell | 299.61 | Amplified | 3+ | 2+ |
| OVA14 | 58 | W | IIIC | Ovary | Serous | 138.87 | Amplified | 3+ | 3+ |
| OVA1 | 64 | W | IA | Ovary | Serous | 63.79 | Not amplified | 2+ | 1+ |
| OVA5 | 60 | W | IIIC | Ovary | Serous | 85.31 | Not amplified | 2+ | 2+ |
| OVA13 | 42 | W | IIIC | Ovary | Clear cell | 54.20 | Not amplified | 2+ | NA***** |
| OVA12 | 32 | W | IC | Ovary | Clear cell | 27.10 | Not amplified | 1+/0 | 0 |
| OVA3 | 53 | W | IIIA | Ovary | Serous | 13.92 | Not amplified | 1+/0 | 0 |
| OVA4 | 64 | W | IIIC | Ovary | Serous | 20.65 | Not amplified | 1+/0 | 1+ |
*
FIGO: International Federation of Gynecology and Obstetrics;
**
MFI: mean fluorescence intensity;
***
FISH: fluorescent in situ hybridization.
****
Primary cell line established from a patient in progression after multiple chemotherapy regimens and confirmed to be highly resistant in vitro by extreme drug resistant (EDR) assay to multiple chemotherapy drugs including paclitaxel (Supplementary Figure 2).
*****
Data Not Available