Table 5. Cost-Effectiveness relative to Next Broadest Strategy, by Sex.

Males	ATP III	ACC-AHA	Age/Sex-Based
Total Additional Persons Acted On	6.11 m	7.37 m	15.9 m
Total Cost	-$7.75 b	-$4.07 b	-$8.02 b
Treatment costs	$5.85 b	$7.33 b	$6.87 b
Screening costs	$1.85 b	$2.23 b	$1.48 b
Savings from events averted	-$13.6 b	-$11.4 b	-$14.9 b
Incident CHD Events Averted	249,000	162,000	263,000
QALYs Saved	178,000	124,600	158,000
Lives Saved	42,900	28,400	27,700
Total Cost per QALY (ICER)	Cost-saving	Cost-saving	Cost-saving
NNT per QALY	35	60	101
NNT per Life Saved	204	260	574
Females	ATP III	ACC-AHA	Age/Sex-Based
Total Additional Persons Acted On	2.65 m	4.91 m	13.0 m
Total Cost	-$2.97 b	$219 m	-$3.43 b
Treatment costs	$2.44 b	$5.98 b	$6.58 b
Screening costs	$800 m	$1.48 b	$1.21 b
Savings from events averted	-$5.41 b	-$5.76 b	-$10.0 b
Incident CHD Events Averted	92,100	74,500	158,000
QALYs Saved	74,900	58,600	110,000
Lives Saved	12,800	14,700	21,400
Total Cost per QALY (ICER)	Cost-saving	$3,400	Cost-saving
NNT per QALY	36	84	118
NNT per Life Saved	206	334	609