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Adverse Events
| Adverse Events | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Total |
|---|---|---|---|---|---|
| Alopecia | 11 | 22 | 0 | 0 | 33 |
| Constipation | 20 | 10 | 1 | 0 | 31 |
| Dermatologic | 14 | 1 | 1 | 0 | 16 |
| Diarrhea | 16 | 1 | 0 | 0 | 17 |
| Fatigue | 27 | 15 | 4 | 0 | 46 |
| Anemia | 21 | 17 | 2 | 0 | 40 |
| Hypertension | 1 | 0 | 0 | 1 | 2 |
| Electrolyte | 12 | 0 | 0 | 0 | 12 |
| Mucositis | 13 | 7 | 0 | 0 | 20 |
| Nausea/vomiting | 24 | 6 | 0 | 0 | 30 |
| GI perforation | 0 | 0 | 0 | 0 | 0 |
| Neurology | 22 | 3 | 0 | 0 | 25 |
| Neutropenia | 5 | 21 | 19 | 5 | 50 |
| Pain | 28 | 3 | 2 | 0 | 33 |
| Thrombocytopenia | 19 | 6 | 2 | 0 | 26 |
| Wound healing | 0 | 0 | 2 | 0 | 2 |
| Other | 44 | 16 | 0 | 0 | 60 |
| Total | 277 | 128 | 33 | 6 | 444 |
