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. 2017 Sep 18;19(11):857–867. doi: 10.1016/j.neo.2017.06.006

Supplementary Figure 4.

Supplementary Figure 4

Genomic alterations in the eight MUC1 network genes within the nine-gene list associate with reductions in DSF and OS in patients with either PC or skin cutaneous melanoma. FAM84B gene was removed from the nine-gene set (APP, CTNNB1, GALNT10, GRB2, LYN, SIGLEC1, SOS1, ZAP70, and FAM84B). The specific genomic alterations (see Table 3 for details) in the remaining eight MUC1 network gene associate with decreases in DFS in PC (A) and cutaneous melanoma (C) as well as OS (B) in cutaneous melanoma. Genomic data were extracted from the TCGA cohorts of PC and skin cutaneous melanoma within the cBioPortal database.