Table 3.
Candidate Genes Selected Using the Training Sets
| Gene | Gen Alta | HRb | 95% CIb | P Valueb | Frequencyc |
|---|---|---|---|---|---|
| GALNT10d, e | Amp Mut | 5.177 | 1.269-21.311 | .022* | 4 |
| SOS1d, e | Amp Mut | 23 | 5.181-98.222 | <.0001* | 10 |
| ZAP70d, e | Amp Mut | 4.524 | 1.765-11.598 | .002* | 5 |
| FAM84Bd, e | Amp | 2.236 | 1.053-4.746 | .036* | 2 |
| GRB2d, e | Amp Mut | 7.696 | 1.031-57.462 | .047* | 3 |
| SIGLEC1d, e | Amp Mut | 6.46 | 1.98-21.074 | .002* | 4 |
| CTNNB1d, e | Amp Mut | 6.553 | 1.883-22.808 | .003* | 5 |
| APCd, e | Homdel Mut | 3.084 | 1.2-7.924 | .019* | 5 |
| LYNd, e | Amp Mut | 2.535 | 0.993-6.471 | .052 | 1 |
| GALNT15d | 7.645 | 1.013-57.701 | .049* | 1 | |
| ERBB2 | 2.464 | 0.614-9.889 | .203 | 1 | |
| CTNND1 | 6.139 | 0.839-44.933 | .074 | 2 | |
| GALNT2 | 1.776 | 0.536-5.888 | .348 | 1 | |
| MUC1 | 0.365 | 0.037-3.597 | .388 | 1 | |
| JUP | 0.017 | 0.009-0.586 | .024* | 1 | |
| ABL1 | 0 | 0-0.005 | 0 | 1 |
a
Genomic alterations are included only for the final set of genes. Amp, amplification; Mut, mutation; Homdel, homdeletion.
b
Best HR, CI, and P value produced in 10 training sets.
c
Number of training sets from which the candidates were selected.
d
Candidates that are evaluated in 10 training sets.
e
The final set of genes or the nine-gene set.