Table.
Global prevalence, incidence, and YLDs for 2016, percentage change of YLD counts, and percentage change of age-standardised YLD rates between 2006 and 2016 for all causes and nine impairments
|
Prevalence in thousands (95% UI) |
Incidence in thousands (95% UI) |
YLDs in thousands (95% UI) |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| 2016 counts | 2016 counts | 2016 counts | Percentage change in counts between 2006 and 2016 | Percentage change in age-standardised rates between 2006 and 2016 | |||||
| All causes | 7 122 683 (7 115 742 to 7 129 084) | 44 245 182 (42 139 690 to 46 565 214)* | 805 393 (601 661 to 1 045 626) | 16·4 (16·0 to 16·9)† | –0·9 (−1·2 to −0·5)† | ||||
| Communicable, maternal, neonatal, and nutritional disorders | 4 943 086 (4 920 138 to 4 967 418) | 25 266 823 (23 366 307 to 27 404 017)* | 101 472 (72 326 to 136 902) | 4·9 (2·7 to 7·3)† | –5·1 (−7·2 to −2·9)† | ||||
| HIV/AIDS and tuberculosis | 2 051 462 (1 904 878 to 2 137 104) | 10 884 (9882 to 12 069)* | 6871 (4846 to 9324) | –3·6 (−15·5 to 7·1) | –16·9 (−27·3 to −7·3)† | ||||
| Tuberculosis | 1 918 597 (1 797 774 to 2 043 357) | 9019 (8052 to 10 157)* | 2839 (1886 to 3843) | 6·3 (4·3 to 8·3)† | –10·6 (−12·0 to −9·1)† | ||||
| Drug-susceptible tuberculosis | 9036 (8134 to 10 108) | 8705 (7755 to 9818) | 2735 (1815 to 3 696) | 6·4 (4·3 to 8·6)† | –10·5 (−12·0 to −8·9)† | ||||
| Multidrug-resistant tuberculosis without extensive drug resistance | 313 (279 to 353) | 296 (261 to 336) | 98 (66 to 136) | –1·0 (−10·1 to 8·9) | –16·9 (−24·5 to −8·7)† | ||||
| Extensively drug-resistant tuberculosis | 19 (17 to 22) | 18 (16 to 21) | 6 (4 to 9) | 181·8 (147·5 to 218·2)† | 135·8 (107·4 to 166·0)† | ||||
| Latent tuberculosis infection | 1 909 229 (1 788 354 to 2 034 184) | ·· | ·· | ·· | ·· | ||||
| HIV/AIDS | 36 369 (34 215 to 39 122) | 1865 (1690 to 2129)‡ | 4032 (2785 to 5587) | –9·5 (−24·9 to 7·8) | –20·9 (−34·7 to −4·9)† | ||||
| Drug-susceptible HIV/AIDS - Tuberculosis | 1076 (760 to 1467) | 1365 (981 to 1847) | 415 (250 to 634) | –20·8 (−24·7 to −17·4)† | –30·0 (−33·4 to −27·0)† | ||||
| Multidrug-resistant HIV/AIDS - Tuberculosis without extensive drug resistance | 28 (18 to 41) | 36 (24 to 52) | 11 (7 to 19) | –27·8 (−39·8 to −15·0)† | –36·2 (−46·7 to −24·9)† | ||||
| Extensively drug-resistant HIV/AIDS - Tuberculosis | 1 (1 to 2) | 1 (1 to 2) | 0 (0 to 1) | 147·8 (107·8 to 195·2)† | 119·0 (84·1 to 161·0)† | ||||
| HIV/AIDS resulting in other diseases | 35 264 (33 138 to 38 026) | 1865 (1690 to 2129) | 3605 (2467 to 5059) | –8·0 (−25·3 to 12·6) | –19·7 (−35·1 to −0·7)† | ||||
| Diarrhoea, lower respiratory infections, and other common infectious diseases | 434 596 (422 500 to 442 782) | 23 240 453 (21 377 295 to 25 359 204)* | 20 656 (14 317 to 28 476) | 7·2 (6·4 to 7·9)† | –3·4 (−4·0 to −2·7)† | ||||
| Diarrhoeal diseases | 66 972 (63 500 to 70 778) | 4 480 401 (4 246 997 to 4 737 769) | 7506 (5176 to 10 240) | 7·5 (6·5 to 8·5)† | –3·6 (−4·4 to −2·7)† | ||||
| Intestinal infectious diseases | 810 (730 to 906) | 15 532 (13 599 to 17 777)* | 125 (84 to 175) | –16·2 (−22·8 to −8·9)† | –22·1 (−28·2 to −15·4)† | ||||
| Typhoid fever | 746 (641 to 863) | 11 774 (10 227 to 13 622) | 114 (75 to 159) | –16·2 (−23·4 to −8·4)† | –22·0 (−28·5 to −14·6)† | ||||
| Paratyphoid fever | 165 (145 to 187) | 3758 (3328 to 4257) | 10 (7 to 15) | –10·9 (−17·7 to −3·6)† | –18·6 (−24·8 to −12·1)† | ||||
| Other intestinal infectious diseases | ·· | ·· | 1 (1 to 2) | –41·0 (−48·3 to −32·8)† | –45·1 (−51·9 to −37·7)† | ||||
| Lower respiratory infections | 8 030 (7 582 to 8 548) | 336 462 (313 085 to 361 622) | 482 (320 to 678) | 22·3 (20·0 to 24·9)† | 7·1 (5·3 to 9·1)† | ||||
| Upper respiratory infections | 235 768 (211 381 to 262 904) | 17 778 134 (15 853 332 to 19 905 351) | 5864 (3475 to 9057) | 9·3 (8·3 to 10·6)† | –1·2 (−1·9 to −0·5)† | ||||
| Otitis media | 106 062 (95 502 to 117 009) | 451 730 (365 179 to 564 104) | 3137 (1948 to 4665) | 2·0 (−0·5 to 4·5) | –5·8 (−8·1 to −3·6)† | ||||
| Meningitis | 14 423 (12 441 to 16 722) | 2821 (2464 to 3310) | 1483 (1039 to 1962) | 10·8 (8·3 to 15·3)† | 0·5 (−2·0 to 5·6) | ||||
| Pneumococcal meningitis | 6180 (5170 to 7365) | 612 (498 to 756) | 634 (445 to 840) | 7·6 (3·9 to 11·8)† | –2·8 (−6·2 to 1·1) | ||||
| H influenzae type B meningitis | 2012 (1592 to 2545) | 397 (291 to 534) | 248 (171 to 330) | –13·8 (−18·5 to −9·5)† | –21·1 (−25·5 to −17·0)† | ||||
| Meningococcal infection | 1661 (1207 to 2270) | 561 (442 to 707) | 168 (113 to 236) | 19·5 (14·1 to 57·7)† | 8·8 (3·1 to 54·0)† | ||||
| Other meningitis | 4571 (3446 to 5833) | 1250 (1056 to 1487) | 432 (296 to 585) | 34·8 (30·3 to 39·7)† | 21·7 (17·6 to 26·1)† | ||||
| Encephalitis | 14 908 (9877 to 21 755) | 6534 (5957 to 7165) | 1651 (1181 to 2145) | 6·0 (3·1 to 8·7)† | –6·5 (−9·1 to −4·2)† | ||||
| Diphtheria | 0 (0 to 0) | 4 (4 to 6) | 0 (0 to 0) | –58·0 (−69·3 to −44·4)† | –61·0 (−71·5 to −47·9)† | ||||
| Whooping cough | 1593 (1242 to 2001) | 11 627 (9069 to 14 610) | 79 (47 to 124) | –22·5 (−25·0 to −19·9)† | –25·1 (−27·6 to −22·6)† | ||||
| Tetanus | 160 (157 to 163) | 90 (51 to 121) | 4 (2 to 6) | –13·0 (−25·8 to 0·5) | –21·3 (−32·8 to −9·3)† | ||||
| Measles | 245 (89 to 532) | 8955 (3251 to 19 426) | 22 (7 to 51) | –62·4 (−66·9 to −57·6)† | –64·0 (−68·3 to −59·4)† | ||||
| Varicella and herpes zoster | 7602 (6996 to 8221) | 148 162 (144 145 to 152 728) | 304 (187 to 468) | 21·4 (18·5 to 24·4)† | 1·6 (−0·3 to 3·7) | ||||
| Neglected tropical diseases and malaria | 1 821 783 (1 778 850 to 1 853 280) | 440 947 (378 282 to 512 509)* | 13 665 (9345 to 19 194) | –10·6 (−15·1 to −6·0)† | –20·0 (−24·2 to −15·8)† | ||||
| Malaria | 128 948 (113 638 to 145 601) | 213 098 (172 037 to 265 778) | 1741 (1289 to 2326) | –11·1 (−15·9 to −6·1)† | –17·2 (−21·9 to −12·5)† | ||||
| Chagas disease | 7201 (6065 to 8514) | 180 (150 to 214) | 63 (41 to 90) | 9·2 (5·6 to 12·7)† | –10·8 (−13·6 to −8·0)† | ||||
| Leishmaniasis | 4835 (4147 to 5523) | 799 (618 to 1021) | 275 (178 to 401) | 26·9 (15·7 to 40·3)† | 10·9 (0·7 to 23·9)† | ||||
| Visceral leishmaniasis | 30 (28 to 32) | 120 (112 to 129) | 2 (1 to 3) | –54·2 (−59·2 to −48·6)† | –59·0 (−63·4 to −54·2)† | ||||
| Cutaneous and mucocutaneous leishmaniasis | 4320 (3650 to 5238) | 678 (497 to 902) | 273 (177 to 399) | 28·6 (16·8 to 42·9)† | 12·5 (1·7 to 26·1)† | ||||
| African trypanosomiasis | 7 (4 to 12) | 5 (4 to 6) | 2 (1 to 4) | –72·5 (−79·1 to −63·6)† | –75·3 (−81·3 to −67·4)† | ||||
| Schistosomiasis | 189 774 (179 771 to 200 083) | 71 385 (67 342 to 76 073) | 1496 (755 to 2815) | –24·5 (−26·0 to −22·5)† | –33·2 (−34·6 to −31·4)† | ||||
| Cysticercosis | 2676 (2232 to 3149) | ·· | 421 (274 to 581) | –4·6 (−11·0 to 1·4) | –19·9 (−25·3 to −15·1)† | ||||
| Cystic echinococcosis | 974 (674 to 1426) | 204 (151 to 304) | 90 (52 to 146) | –38·3 (−59·3 to −1·7)† | –45·6 (−64·1 to −14·2)† | ||||
| Lymphatic filariasis | 29 382 (24 770 to 36 117) | 7604 (6561 to 8750) | 1189 (588 to 2115) | –37·3 (−52·4 to −26·0)† | –45·3 (−58·4 to −35·5)† | ||||
| Onchocerciasis | 14 650 (9474 to 24 168) | 3839 (1747 to 7518) | 962 (452 to 1672) | –24·0 (−41·6 to −6·5)† | –32·6 (−48·5 to −17·5)† | ||||
| Trachoma | 3338 (2 439 to 4492) | ·· | 245 (162 to 354) | –0·5 (−6·5 to 5·2) | –23·8 (−28·5 to −19·3)† | ||||
| Dengue | 6046 (3292 to 10 244) | 101 064 (61 458 to 153 334) | 982 (433 to 1829) | 74·7 (42·5 to 293·7)† | 58·4 (29·3 to 256·7)† | ||||
| Yellow fever | 3 (1 to 8) | 112 (32 to 283) | 0 (0 to 0) | –18·1 (−30·1 to −3·5)† | –24·2 (−35·0 to −10·9)† | ||||
| Rabies | 0 (0 to 1) | 13 (7 to 19) | 0 (0 to 0) | –46·7 (−56·0 to −33·4)† | –52·8 (−61·1 to −40·9)† | ||||
| Intestinal nematode infections | 1 507 853 (1 450 985 to 1 542 581) | ·· | 2946 (1713 to 4804) | –14·4 (−18·0 to −10·3)† | –22·7 (−26·0 to −18·9)† | ||||
| Ascariasis | 799 683 (737 609 to 872 087) | ·· | 924 (498 to 1 550) | –26·7 (−33·0 to −19·8)† | –33·7 (−39·5 to −27·5)† | ||||
| Trichuriasis | 435 095 (410 564 to 464 463) | ·· | 337 (186 to 574) | –20·0 (−27·9 to −11·6)† | –27·8 (−34·9 to −20·2)† | ||||
| Hookworm disease | 450 683 (424 863 to 479 224) | ·· | 1685 (1002 to 2649) | –4·2 (−9·5 to 1·3) | –13·5 (−18·3 to −8·5)† | ||||
| Food-borne trematodiases | 74 725 (70 800 to 78 800) | 34 989 (23 062 to 45 803) | 1771 (924 to 3158) | 6·7 (1·3 to 15·7)† | –7·0 (−11·4 to 0·5) | ||||
| Leprosy | 523 (499 to 547) | 55 (53 to 58) | 32 (21 to 44) | 1·2 (−1·3 to 3·6) | –18·1 (−20·0 to −16·2)† | ||||
| Ebola virus disease | 1 (0 to 4) | 0 (0 to 0) | 0 (0 to 1) | ·· | ·· | ||||
| Zika virus disease | 129 (97 to 179) | 7598 (5696 to 10 664) | 4 (3 to 6) | ·· | ·· | ||||
| Guinea worm disease | 0 (0 to 0) | 0 (0 to 0) | 0 (0 to 0) | –99·5 (−99·7 to −99·4)† | –99·6 (−99·7 to −99·5)† | ||||
| Other neglected tropical diseases | 49 493 (47 574 to 51 781) | ·· | 1 445 (943 to 2094) | 6·0 (3·6 to 8·2)† | –0·6 (−2·9 to 1·4) | ||||
| Maternal disorders | 8730 (8105 to 9254) | 118 296 (104 358 to 137 177)* | 852 (589 to 1181) | –5·8 (−18·4 to 10·1) | –14·6 (−25·8 to −0·2)† | ||||
| Maternal haemorrhage | 1403 (1155 to 1706) | 9626 (7835 to 11 884) | 60 (39 to 87) | 3·3 (−19·8 to 32·5) | –5·7 (−26·6 to 21·4) | ||||
| Maternal sepsis and other pregnancy related infections | 1662 (1256 to 2201) | 10 377 (8385 to 13 151) | 46 (23 to 83) | 2·7 (−46·0 to 98·1) | –5·6 (−50·1 to 83·4) | ||||
| Maternal hypertensive disorders | 4449 (2947 to 6101) | 20 811 (18 216 to 23 245) | 216 (120 to 349) | 7·8 (−32·0 to 71·7) | –0·9 (−37·4 to 57·6) | ||||
| Maternal obstructed labour and uterine rupture | 1041 (868 to 1229) | 7238 (5821 to 9042) | 336 (218 to 472) | –13·7 (−20·1 to −7·4)† | –22·6 (−28·2 to −17·0)† | ||||
| Maternal abortion, miscarriage, and ectopic pregnancy | 576 (371 to 820) | 70 245 (56 320 to 88 126) | 63 (35 to 102) | –4·4 (−40·1 to 49·9) | –12·8 (−45·4 to 37·1) | ||||
| Other maternal disorders | ·· | ·· | 131 (90 to 181) | –10·4 (−22·4 to 4·8) | –18·6 (−29·3 to −4·8)† | ||||
| Neonatal disorders | 80 244 (73 591 to 86 593) | ·· | 13 737 (9642 to 19 774) | 21·4 (9·0 to 36·3)† | 11·4 (0·0 to 25·1)† | ||||
| Neonatal preterm birth complications | 66 092 (55 818 to 78 007) | ·· | 8328 (5727 to 11 880) | 18·4 (−0·6 to 41·3) | 8·5 (−9·0 to 29·6) | ||||
| Neonatal encephalopathy due to birth asphyxia and trauma | 12 134 (7668 to 19 247) | ·· | 1596 (594 to 3694) | 30·9 (21·6 to 46·0)† | 18·9 (11·0 to 31·4)† | ||||
| Neonatal sepsis and other neonatal infections | 6653 (2712 to 15 058) | ·· | 2647 (893 to 6765) | 29·7 (22·6 to 39·5)† | 19·5 (13·1 to 28·3)† | ||||
| Haemolytic disease and other neonatal jaundice | 2093 (1861 to 2337) | ·· | 654 (498 to 822) | 19·9 (16·0 to 23·5)† | 9·5 (6·0 to 12·9)† | ||||
| Other neonatal disorders | ·· | ·· | 512 (351 to 767) | 7·0 (−3·7 to 19·2) | 2·7 (−7·6 to 14·4) | ||||
| Nutritional deficiencies | 1 673 391 (1 633 390 to 1 689 822) | 598 813 (516 074 to 717 722)* | 41 431 (27 722 to 58 560) | 6·4 (5·2 to 7·7)† | –2·6 (−3·7 to −1·5)† | ||||
| Protein-energy malnutrition | 63 135 (62 102 to 64 196) | 43 590 (42 935 to 44 253) | 3205 (2067 to 4487) | 8·3 (3·4 to 13·3)† | 3·9 (−0·8 to 8·7) | ||||
| Iodine deficiency | 119 214 (105 724 to 133 961) | 3043 (2708 to 3411) | 3138 (2126 to 4398) | –6·1 (−7·6 to −4·4)† | –16·9 (−18·4 to −15·4)† | ||||
| Vitamin A deficiency | 508 801 (445 148 to 601 630) | 552 180 (469 062 to 671 144) | 252 (159 to 388) | 12·0 (8·7 to 15·5)† | 2·6 (−0·3 to 5·6) | ||||
| Iron-deficiency anaemia | 1 244 781 (1 205 796 to 1 284 426) | ·· | 34 727 (22 960 to 49 579) | 7·5 (6·2 to 8·9)† | –1·8 (−3·0 to −0·5)† | ||||
| Other nutritional deficiencies | ·· | ·· | 109 (70 to 152) | 8·5 (3·4 to 13·8)† | 3·8 (−1·0 to 8·9) | ||||
| Other communicable, maternal, neonatal, and nutritional diseases | 1 728 266 (1 680 548 to 1 764 134) | 857 430 (713 393 to 1 035 256) | 4166 (2686 to 6243) | 10·9 (8·4 to 13·1)† | –0·6 (−2·7 to 1·3) | ||||
| Sexually transmitted diseases excluding HIV | 1 175 931 (1 131 754 to 1 217 694) | 552 776 (499 026 to 612 824) | 2546 (1628 to 3983) | 15·7 (13·9 to 17·7)† | 1·9 (0·3 to 3·7)† | ||||
| Syphilis | 56 092 (44 184 to 70 172) | 38 838 (29 431 to 50 913) | 188 (133 to 249) | 29·2 (25·5 to 32·6)† | 3·5 (1·1 to 6·0)† | ||||
| Chlamydial infection | 93 574 (75 600 to 114 406) | 73 667 (59 690 to 90 358) | 516 (324 to 804) | 10·2 (8·1 to 12·1)† | –1·3 (−3·1 to 0·3) | ||||
| Gonococcal infection | 57 124 (46 375 to 70 820) | 190 766 (147 718 to 242 152) | 548 (341 to 851) | 23·5 (19·4 to 27·6)† | 10·5 (6·7 to 14·2)† | ||||
| Trichomoniasis | 171 779 (148 048 to 196 705) | 148 908 (126 821 to 171 971) | 198 (76 to 421) | 15·9 (14·8 to 17·1)† | 1·8 (0·9 to 2·7)† | ||||
| Genital herpes | 859 580 (748 108 to 991 917) | 57 156 (49 205 to 67 554) | 221 (71 to 507) | 17·8 (15·5 to 19·7)† | –0·2 (−1·6 to 1·5) | ||||
| Other sexually transmitted diseases | 36 588 (31 753 to 40 490) | 43 441 (37 364 to 50 632) | 875 (576 to 1284) | 11·5† (9·3 to 13·8) | –0·9 (−3·0 to 1·2) | ||||
| Hepatitis | 640 226 (566 219 to 731 671) | 304 644 (182 678 to 477 007) | 280 (175 to 413) | –20·9 (−33·6 to −5·7)† | –29·2† (−40·2 to −16·3) | ||||
| Acute hepatitis A | 12 270 (3 159 to 25 111) | 159 516 (41 071 to 326 448) | 72 (39 to 119) | –29·0 (−60·7 to 27·6) | –35·1 (−63·2 to 14·6) | ||||
| Hepatitis B | 468 435 (396 824 to 554 418) | 118 976 (92 788 to 152 775) | 165 (99 to 261) | –16·3 (−28·6 to −2·3)† | –26·7 (−36·7 to −14·9)† | ||||
| Hepatitis C | 158 055 (141 445 to 175 144) | 7094 (6474 to 7724) | 6 (3 to 12) | 5·1 (−0·4 to 11·4) | –5·3 (−10·4 to 0·8) | ||||
| Acute hepatitis E | 1466 (1308 to 1645) | 19 058 (17 003 to 21 385) | 36 (23 to 54) | –25·7 (−32·1 to −19·0)† | –30·8 (−36·6 to −24·7)† | ||||
| Other infectious diseases | 44 426 (42 785 to 46 296) | 9 (6 to 13) | 1 340 (879 to 1946) | 11·5 (9·5 to 13·7)† | 3·5 (1·6 to 5·7)† | ||||
| Non-communicable diseases | 6 681 939 (6 668 902 to 6 695 003) | 18 358 708 (17 561 181 to 19 263 162)* | 648 563 (481 335 to 836 494) | 17·9 (17·5 to 18·4)† | –0·4 (−0·7 to −0·1)† | ||||
| Neoplasms | 42 986 (42 692 to 43 241) | 17 228 (16 713 to 17 802) | 5180 (3830 to 6697) | 30·5 (28·1 to 33·9)† | 1·2 (−0·6 to 3·8) | ||||
| Lip and oral cavity cancer | 1387 (1 346 to 1 425) | 382 (371 to 392) | 142 (103 to 186) | 32·7 (27·8 to 37·4)† | 3·6 (−0·3 to 7·0) | ||||
| Nasopharynx cancer | 332 (314 to 352) | 96 (91 to 101) | 40 (28 to 53) | 8·4 (0·5 to 15·9)† | –11·2 (−17·5 to −5·3)† | ||||
| Other pharynx cancer | 478 (452 to 494) | 170 (159 to 176) | 58 (42 to 76) | 36·7 (26·9 to 43·2)† | 5·8 (−1·7 to 10·8) | ||||
| Oesophageal cancer | 556 (539 to 577) | 443 (433 to 456) | 112 (79 to 144) | 9·1 (5·4 to 13·7)† | –16·2 (−19·0 to −12·8)† | ||||
| Stomach cancer | 2199 (2144 to 2255) | 1157 (1134 to 1180) | 300 (218 to 384) | 17·9 (14·6 to 21·5)† | –9·1 (−11·7 to −6·4)† | ||||
| Colon and rectum cancer | 6323 (6112 to 6632) | 1716 (1658 to 1795) | 599 (442 to 780) | 34·0 (28·4 to 41·1)† | 1·7 (−2·4 to 7·1) | ||||
| Liver cancer | 1027 (974 to 1076) | 1008 (953 to 1042) | 228 (163 to 298) | 42·9 (36·6 to 49·9)† | 11·4 (6·7 to 16·8)† | ||||
| Liver cancer due to hepatitis B | 599 (516 to 675) | 436 (380 to 488) | 98 (68 to 131) | 41·0 (33·4 to 50·8)† | 11·3 (5·3 to 19·0)† | ||||
| Liver cancer due to hepatitis C | 261 (236 to 286) | 189 (170 to 207) | 43 (31 to 58) | 41·7 (35·4 to 47·7)† | 8·0 (3·3 to 12·6)† | ||||
| Liver cancer due to alcohol use | 186 (157 to 216) | 148 (125 to 171) | 34 (23 to 46) | 48·4 (37·0 to 62·2)† | 13·9 (5·1 to 24·6)† | ||||
| Liver cancer due to other causes | 326 (288 to 371) | 235 (210 to 264) | 54 (38 to 71) | 44·0 (35·2 to 52·5)† | 13·2 (6·4 to 19·8)† | ||||
| Gallbladder and biliary tract cancer | 169 (152 to 179) | 184 (168 to 193) | 41 (29 to 54) | 21·3 (16·2 to 26·8)† | –7·9 (−11·8 to −3·7)† | ||||
| Pancreatic cancer | 364 (349 to 375) | 418 (406 to 425) | 86 (60 to 111) | 33·8 (29·2 to 37·5)† | 1·8 (−1·8 to 4·7) | ||||
| Larynx cancer | 638 (627 to 653) | 187 (184 to 191) | 75 (55 to 98) | 22·8 (19·3 to 26·5)† | –5·6 (−8·3 to −2·8)† | ||||
| Tracheal, bronchus, and lung cancer | 2836 (2750 to 2920) | 2008 (1958 to 2055) | 474 (345 to 598) | 30·2 (26·1 to 33·9)† | 0·1 (−3·0 to 3·0) | ||||
| Malignant skin melanoma | 1347 (1156 to 1506) | 282 (243 to 314) | 90 (63 to 123) | 37·9 (31·7 to 42·7)† | 8·8 (3·8 to 12·6)† | ||||
| Non-melanoma skin cancer | 853 (682 to 1066) | 1521 (1109 to 2008) | 31 (17 to 52) | 5·8 (−3·3 to 19·7) | –21·4 (−28·0 to −10·8)† | ||||
| Non-melanoma skin cancer (squamous-cell carcinoma) | 690 (415 to 996) | 635 (386 to 922) | 30 (16 to 51) | 5·2 (−4·1 to 19·5) | –21·8 (−28·6 to −11·1)† | ||||
| Non-melanoma skin cancer (basal-cell carcinoma) | 103 (65 to 167) | 886 (574 to 1 262) | 1 (0 to 2) | 23·8 (16·1 to 31·7)† | –5·6 (−11·5 to 0·4) | ||||
| Breast cancer | 8151 (7808 to 8610) | 1702 (1629 to 1801) | 739 (535 to 982) | 26·9 (20·6 to 34·5)† | –1·4 (−6·2 to 4·1) | ||||
| Cervical cancer | 1939 (1544 to 2082) | 511 (414 to 542) | 186 (128 to 247) | 9·4 (2·7 to 18·3)† | –11·3 (−16·7 to −4·3)† | ||||
| Uterine cancer | 1959 (1882 to 2076) | 417 (401 to 442) | 150 (107 to 201) | 39·8 (32·9 to 50·0)† | 7·2 (2·1 to 15·0)† | ||||
| Ovarian cancer | 786 (743 to 809) | 254 (242 to 260) | 116 (84 to 150) | 24·1 (16·9 to 29·4)† | –2·7 (−8·3 to 1·3) | ||||
| Prostate cancer | 5697 (5098 to 6714) | 1436 (1293 to 1619) | 533 (384 to 707) | 39·0 (32·3 to 48·1)† | 4·4 (−0·7 to 11·4) | ||||
| Testicular cancer | 340 (328 to 355) | 67 (64 to 70) | 24 (17 to 32) | 29·8 (24·0 to 35·9)† | 12·8 (7·8 to 18·2)† | ||||
| Kidney cancer | 1289 (1226 to 1329) | 342 (331 to 350) | 114 (83 to 150) | 27·7 (23·5 to 31·1)† | 0·0 (−3·3 to 2·6) | ||||
| Bladder cancer | 1767 (1721 to 1813) | 437 (427 to 448) | 165 (121 to 217) | 31·1 (26·9 to 35·1)† | –0·6 (−3·7 to 2·5) | ||||
| Brain and nervous system cancer | 781 (693 to 818) | 330 (299 to 349) | 106 (75 to 139) | 37·9 (33·1 to 43·3)† | 12·7 (8·8 to 17·2)† | ||||
| Thyroid cancer | 1234 (1187 to 1313) | 238 (229 to 253) | 80 (56 to 110) | 48·4 (41·5 to 58·2)† | 17·9 (12·6 to 25·7)† | ||||
| Mesothelioma | 53 (49 to 56) | 35 (32 to 36) | 11 (8 to 15) | 27·7 (21·6 to 32·5)† | –1·0 (−5·8 to 2·6) | ||||
| Hodgkin's lymphoma | 291 (264 to 322) | 73 (66 to 82) | 29 (21 to 39) | 10·2 (7·3 to 13·2)† | –6·8 (−9·3 to −4·1)† | ||||
| Non-Hodgkin lymphoma | 1670 (1545 to 1746) | 461 (428 to 482) | 147 (107 to 193) | 45·2 (38·0 to 49·0)† | 13·8 (8·1 to 16·8)† | ||||
| Multiple myeloma | 358 (305 to 398) | 138 (121 to 156) | 70 (49 to 91) | 42·8 (36·8 to 49·4)† | 8·6 (4·1 to 13·7)† | ||||
| Leukaemia | 1675 (1511 to 1765) | 467 (423 to 488) | 214 (153 to 284) | 25·3 (18·7 to 32·2)† | 2·1 (−3·1 to 7·5) | ||||
| Acute lymphoid leukaemia | 292 (256 to 310) | 76 (66 to 80) | 36 (25 to 49) | 31·1 (12·6 to 41·6)† | 16·6 (0·7 to 25·8)† | ||||
| Chronic lymphoid leukaemia | 460 (430 to 496) | 105 (98 to 113) | 57 (41 to 74) | 37·4 (31·6 to 44·6)† | 4·3 (0·0 to 9·5)† | ||||
| Acute myeloid leukaemia | 160 (142 to 169) | 103 (91 to 108) | 29 (20 to 39) | 32·8 (24·5 to 37·6)† | 8·8 (2·2 to 12·6)† | ||||
| Chronic myeloid leukaemia | 92 (84 to 99) | 32 (29 to 34) | 12 (8 to 16) | 6·5 (1·9 to 11·0)† | –15·4 (−18·9 to −12·2)† | ||||
| Other leukaemia | 672 (565 to 722) | 150 (127 to 161) | 81 (57 to 107) | 16·3 (8·5 to 25·5)† | –3·7 (−9·9 to 3·7) | ||||
| Other neoplasms | 2632 (2377 to 2720) | 750 (682 to 772) | 221 (160 to 292) | 51·8 (44·9 to 56·7)† | 21·7 (16·1 to 25·7)† | ||||
| Cardiovascular diseases | 469 454 (462 582 to 474 872) | 54 120 (51 965 to 56 447)* | 33 482 (24 477 to 43 376) | 29·4 (26·7 to 31·9)† | 1·0 (−1·1 to 2·9) | ||||
| Rheumatic heart disease | 29 677 (26 737 to 32 927) | 1196 (1095 to 1308) | 1456 (931 to 2116) | 17·3 (13·9 to 20·6)† | 3·4 (0·4 to 6·4)† | ||||
| Ischaemic heart disease | 153 533 (145 992 to 160 779) | 20 731 (19 530 to 22 072) | 6916 (4812 to 9385) | 29·3 (28·5 to 30·1)† | 0·5 (−0·1 to 1·1) | ||||
| Cerebrovascular disease | 79 574 (77 057 to 82 118) | 13 677 (12 714 to 14 692)§ | 14 452 (10 150 to 18 414) | 33·5 (27·3 to 39·2)† | 2·7 (−2·0 to 7·1) | ||||
| Ischaemic stroke | 67 595 (60 812 to 74 572) | 9556 (8655 to 10 513)§ | 11 802 (8246 to 15 151) | 35·2 (27·8 to 42·2)† | 3·7 (−2·1 to 9·0) | ||||
| Haemorrhagic stroke | 15 310 (13 857 to 16 954) | 4120 (3764 to 4508)§ | 2650 (1896 to 3381) | 26·6 (20·1 to 32·9)† | –1·6 (−6·6 to 3·4) | ||||
| Hypertensive heart disease | 17 190 (14 948 to 19 774) | ·· | 1380 (959 to 1 894) | 31·6 (29·7 to 33·5)† | 0·4 (−0·8 to 1·6) | ||||
| Cardiomyopathy and myocarditis | 6118 (5779 to 6416) | 2483 (2217 to 2784)* | 559 (384 to 786) | 18·7 (16·8 to 20·7)† | –4·0 (−5·4 to −2·6)† | ||||
| Myocarditis | 1786 (1607 to 1977) | 2483 (2217 to 2784) | 133 (89 to 188) | 13·1 (11·1 to 15·1)† | –1·4 (−2·9 to 0·0)† | ||||
| Alcoholic cardiomyopathy | 1165 (994 to 1359) | ·· | 97 (66 to 138) | 20·6 (15·6 to 25·7)† | –5·4 (−9·0 to −1·7)† | ||||
| Other cardiomyopathy | 4005 (3534 to 4525) | ·· | 329 (226 to 462) | 20·6 (18·3 to 22·9)† | –4·5 (−6·1 to −2·9)† | ||||
| Atrial fibrillation and flutter | 46 311 (41 441 to 52 014) | 3841 (3379 to 4388) | 3614 (2439 to 5024) | 32·0 (30·9 to 33·0)† | 0·3 (−0·4 to 1·0) | ||||
| Peripheral vascular disease | 120 145 (105 640 to 137 704) | 11 020 (9557 to 12 778) | 520 (244 to 941) | 25·5 (23·8 to 27·3)† | –5·9 (−6·8 to −5·0)† | ||||
| Endocarditis | 500 (448 to 568) | 1172 (1068 to 1280) | 40 (27 to 55) | 23·0 (20·5 to 25·6)† | –3·7 (−5·6 to −1·9)† | ||||
| Other cardiovascular and circulatory diseases | 87 122 (76 311 to 98 866) | ·· | 4546 (3102 to 6404) | 20·6† (18·7 to 22·6) | –2·2† (−3·4 to −1·0) | ||||
| Chronic respiratory diseases | 571 426 (560 139 to 582 621) | 94 696 (90 108 to 99 441)* | 30 954 (25 068 to 37 362) | 24·0 (22·3 to 26·1)† | 3·0 (1·8 to 4·2)† | ||||
| Chronic obstructive pulmonary disease | 251 631 (241 958 to 261 129) | 18 721 (18 004 to 19 456) | 16 288 (14 342 to 17 878) | 28·8 (26·2 to 31·4)† | 1·4 (−0·6 to 3·5) | ||||
| Pneumoconiosis | 1111 (1043 to 1184) | 99 (93 to 105) | 162 (111 to 224) | 32·0 (29·0 to 35·1)† | 1·5 (−0·8 to 3·9) | ||||
| Silicosis | 421 (380 to 464) | 44 (41 to 49) | 60 (41 to 84) | 31·8 (26·1 to 37·1)† | 1·0 (−3·2 to 4·8) | ||||
| Asbestosis | 152 (138 to 170) | 12 (11 to 13) | 23 (16 to 32) | 26·9 (24·3 to 29·6)† | –1·3 (−3·3 to 0·9) | ||||
| Coal workers pneumoconiosis | 294 (256 to 340) | 21 (19 to 24) | 42 (28 to 60) | 34·5 (27·0 to 42·4)† | 2·6 (−3·0 to 8·6) | ||||
| Other pneumoconiosis | 243 (210 to 277) | 21 (18 to 24) | 36 (24 to 50) | 32·5 (27·6 to 37·8)† | 2·8 (−1·0 to 7·0) | ||||
| Asthma | 339 440 (319 582 to 360 796) | 75 496 (71 071 to 80 177) | 13 221 (8726 to 18 839) | 17·2 (16·0 to 18·4)† | 3·6 (2·5 to 4·6)† | ||||
| Interstitial lung disease and pulmonary sarcoidosis | 3978 (3632 to 4352) | 379 (348 to 412) | 416 (282 to 596) | 28·9 (26·7 to 31·2)† | 1·7 (0·3 to 3·1)† | ||||
| Other chronic respiratory diseases | ·· | ·· | 866 (752 to 955) | 49·7 (46·2 to 53·0)† | 34·2 (31·1 to 37·3)† | ||||
| Cirrhosis and other chronic liver diseases | 45 783 (43 781 to 47 831) | 1638 (1575 to 1708) | 1574 (1094 to 2165) | 21·0 (19·4 to 22·6)† | 1·8 (0·5 to 3·0)† | ||||
| Cirrhosis and other chronic liver diseases due to hepatitis B | 12 482 (11 611 to 13 474) | 457 (421 to 500) | 394 (274 to 545) | 26·6 (24·1 to 29·4)† | 2·9 (1·0 to 4·9)† | ||||
| Cirrhosis and other chronic liver diseases due to hepatitis C | 10 903 (9925 to 11 984) | 387 (353 to 426) | 314 (215 to 433) | 26·4 (23·6 to 29·2)† | 2·2 (0·1 to 4·3)† | ||||
| Cirrhosis and other chronic liver diseases due to alcohol use | 11 392 (10 521 to 12 386) | 404 (373 to 439) | 314 (220 to 431) | 25·8 (23·1 to 28·6)† | 0·2 (−1·7 to 2·4) | ||||
| Cirrhosis and other chronic liver diseases due to other causes | 11 007 (10 105 to 11 958) | 391 (363 to 421) | 552 (376 to 772) | 12·3 (10·0 to 14·6)† | 1·7 (−0·4 to 3·7) | ||||
| Digestive diseases | 262 283 (257 495 to 266 222) | 211 761 (201 555 to 223 065)* | 7287 (5169 to 9878) | 27·4 (24·7 to 30·3)† | 5·9 (4·0 to 8·0)† | ||||
| Peptic ulcer disease | 74 335 (69 108 to 80 393) | 10 329 (9 391 to 11 368) | 1364 (891 to 2024) | 38·7 (34·1 to 43·4)† | 14·1 (10·5 to 17·7)† | ||||
| Gastritis and duodenitis | 123 619 (112 199 to 135 163) | 77 140 (70 074 to 85 452) | 1672 (1094 to 2419) | 38·6 (34·5 to 42·9)† | 14·0 (10·9 to 17·2)† | ||||
| Appendicitis | 857 (796 to 922) | 22 580 (20 993 to 24 258) | 263 (176 to 360) | 9·8 (6·5 to 13·2)† | 0·1 (−2·8 to 2·9) | ||||
| Paralytic ileus and intestinal obstruction | 170 (155 to 186) | 4651 (4265 to 5080) | 54 (36 to 74) | 25·2 (23·1 to 27·2)† | 4·9 (3·6 to 6·3)† | ||||
| Inguinal, femoral, and abdominal hernia | 51 239 (46 088 to 56 543) | 36 240 (31 967 to 40 531) | 2152 (1471 to 2993) | 15·3 (12·9 to 17·6)† | –3·1 (−4·8 to −1·7)† | ||||
| Inflammatory bowel disease | 6007 (5622 to 6446) | 3518 (3275 to 3779) | 863 (596 to 1185) | 26·8 (24·0 to 29·6)† | 3·8 (1·8 to 5·9)† | ||||
| Vascular intestinal disorders | 104 (93 to 115) | 583 (527 to 644) | 32 (21 to 43) | 25·7 (21·5 to 30·0)† | 0·2 (−3·3 to 3·5) | ||||
| Gallbladder and biliary diseases | 17 269 (15 618 to 19 012) | 51 509 (46 439 to 56 953) | 231 (158 to 325) | 29·2 (25·4 to 32·7)† | 4·9 (2·4 to 7·4)† | ||||
| Pancreatitis | 584 (532 to 639) | 5210 (4769 to 5703) | 73 (49 to 102) | 29·3 (25·1 to 33·7)† | 5·8 (2·4 to 9·1)† | ||||
| Other digestive diseases | ·· | ·· | 584 (413 to 784) | 32·4 (29·4 to 35·6)† | 10·1 (8·2 to 12·2)† | ||||
| Neurological disorders | 2 595 647 (2 542 097 to 2 651 997) | 1 183 726 (1 021 730 to 1 362 193) | 69 426 (47 199 to 92 890) | 16·3 (14·5 to 18·3)† | 0·4 (−1·0 to 2·0) | ||||
| Alzheimer's disease and other dementias | 43 836 (37 756 to 51 028) | 7779 (6620 to 9135) | 6415 (4506 to 8491) | 38·2 (36·4 to 39·9)† | 0·7 (−0·3 to 1·6) | ||||
| Parkinson's disease | 6063 (4972 to 7325) | 696 (564 to 850) | 706 (457 to 974) | 36·3 (33·6 to 38·6)† | 3·3 (1·6 to 4·8)† | ||||
| Epilepsy | 23 962 (20 402 to 27 737) | 2 761 (2 308 to 3 268) | 7547 (5111 to 10 458) | 8·8 (−2·1 to 22·0) | –2·6 (−12·3 to 9·2) | ||||
| Multiple sclerosis | 2221 (2034 to 2437) | 69 (63 to 76) | 584 (411 to 764) | 24·5 (21·9 to 26·9)† | 3·0 (0·8 to 5·1)† | ||||
| Motor neuron disease | 331 (300 to 367) | 58 (52 to 63) | 70 (49 to 93) | 21·2 (19·5 to 23·1)† | 1·1 (0·1 to 2·1)† | ||||
| Migraine | 1 044 772 (999 535 to 1 087 969) | 110 316 (105 270 to 115 834) | 45 122 (29 046 to 62 827) | 14·3 (13·7 to 14·9)† | 0·1 (−0·2 to 0·5) | ||||
| Tension-type headache | 1 890 670 (1 707 786 to 2 097 762) | 1 061 998 (899 411 to 1 241 310) | 7195 (4615 to 10 500) | 15·4 (13·7 to 17·0)† | 0·4 (−0·4 to 1·4) | ||||
| Other neurological disorders | 24 (16 to 33) | 48 (32 to 66) | 1786 (1212 to 2436) | 30·1 (18·7 to 43·7)† | 17·4 (7·4 to 30·2)† | ||||
| Mental and substance use disorders | 1 111 147 (1 095 612 to 1 128 948) | 410 091 (385 617 to 437 586)* | 150 476 (109 498 to 194 542) | 12·9 (12·4 to 13·5)† | –1·4 (−1·8 to −1·0)† | ||||
| Schizophrenia | 20 883 (18 497 to 23 422) | 1139 (1006 to 1287) | 13 414 (9859 to 16 714) | 16·7 (15·5 to 18·0)† | –0·9 (−1·7 to −0·2)† | ||||
| Alcohol use disorders | 100 389 (89 592 to 111 659) | 50 432 (44 249 to 56 797) | 10 031 (6 883 to 13 787) | 9·7 (7·7 to 11·8)† | –4·8 (−6·7 to −3·1)† | ||||
| Drug use disorders | 61 968 (60 342 to 63 579) | 7460 (6810 to 8140) | 14 607 (10 464 to 19 045) | 15·5 (13·7 to 17·3)† | 1·4 (−0·2 to 3·0) | ||||
| Opioid use disorders | 26 834 (23 563 to 30 952) | 2795 (2443 to 3226) | 11 132 (7725 to 14 577) | 18·0 (15·8 to 20·1)† | 2·7 (0·7 to 4·6)† | ||||
| Cocaine use disorders | 5840 (5322 to 6473) | 347 (304 to 391) | 797 (501 to 1141) | 11·8 (10·0 to 13·6)† | –1·4 (−2·9 to 0·2) | ||||
| Amphetamine use disorders | 4955 (3693 to 6490) | 440 (330 to 577) | 658 (386 to 1038) | 3·7 (0·4 to 6·8)† | –4·0 (−7·3 to −0·9)† | ||||
| Cannabis use disorders | 22 094 (18 965 to 25 856) | 3183 (2706 to 3776) | 647 (401 to 946) | 3·7 (1·2 to 6·0)† | –4·2 (−5·9 to −2·4)† | ||||
| Other drug use disorders | 3944 (3537 to 4362) | 695 (624 to 770) | 1373 (919 to 1912) | 10·6 (8·2 to 13·1)† | –1·5 (−3·6 to 0·7) | ||||
| Depressive disorders | 268 172 (260 480 to 274 698) | 274 704 (251 855 to 300 436) | 44 208 (30 573 to 59 878) | 13·2 (12·2 to 14·4)† | –3·6 (−4·3 to −2·9)† | ||||
| Major depressive disorder | 167 836 (153 908 to 183 754) | 257 768 (234 546 to 284 665) | 34 105 (23 470 to 46 039) | 11·2 (10·1 to 12·3)† | –4·9 (−5·6 to −4·1)† | ||||
| Dysthymia | 105 580 (92 588 to 120 440) | 16 935 (14 981 to 19 313) | 10 104 (6 861 to 14 612) | 20·5 (18·3 to 23·2)† | 1·0 (−0·5 to 2·7) | ||||
| Bipolar disorder | 43 908 (38 383 to 50 196) | 3777 (3313 to 4331) | 8954 (5588 to 13 186) | 14·9 (13·8 to 16·0)† | 0·8 (0·2 to 1·4)† | ||||
| Anxiety disorders | 274 615 (255 323 to 294 796) | 42 407 (39 560 to 45 513) | 26 417 (18 440 to 35 634) | 13·1 (11·9 to 14·3)† | –0·7 (−1·7 to 0·2) | ||||
| Eating disorders | 10 523 (9368 to 11 716) | 5440 (4039 to 7186) | 2148 (1386 to 3091) | 17·3 (15·5 to 19·0)† | 9·1 (7·9 to 10·4)† | ||||
| Anorexia nervosa | 2606 (1932 to 3450) | 897 (665 to 1183) | 556 (338 to 830) | 12·2 (9·7 to 14·7)† | 6·2 (4·0 to 8·4)† | ||||
| Bulimia nervosa | 7559 (5765 to 9931) | 4543 (3169 to 6256) | 1592 (972 to 2392) | 19·2 (16·9 to 21·2)† | 10·2 (8·7 to 11·7)† | ||||
| Autistic spectrum disorders | 62 174 (59 625 to 64 557) | 450 (307 to 624) | 9026 (6119 to 12 681) | 11·4 (10·8 to 12·0)† | 0·3 (−0·2 to 0·8) | ||||
| Autism | 18 302 (15 766 to 21 177) | 51 (26 to 86) | 4649 (2977 to 6699) | 11·3 (10·3 to 12·3)† | –0·1 (−0·9 to 0·8) | ||||
| Asperger syndrome and other autistic spectrum disorders | 43 798 (36 425 to 52 403) | 399 (258 to 572) | 4377 (2864 to 6393) | 11·5 (10·9 to 12·1)† | 0·6 (0·2 to 1·1)† | ||||
| Attention-deficit or hyperactivity disorder | 62 624 (57 564 to 68 596) | 2872 (2562 to 3294) | 755 (452 to 1197) | 6·1 (5·0 to 7·1)† | –0·5 (−1·4 to 0·4) | ||||
| Conduct disorder | 49 005 (40 946 to 57 034) | 16 887 (13 566 to 20 196) | 5947 (3 702 to 8 998) | 2·2 (0·9 to 3·4)† 2·3 | (1·1 to 3·4)† | ||||
| Idiopathic developmental intellectual disability | 114 797 (69 506 to 161 353) | ·· | 4611 (2202 to 7932) | 2·5 (−0·9 to 4·6) | –6·9 (−10·0 to −4·9)† | ||||
| Other mental and substance use disorders | 139 505 (122 047 to 160 430) | 4523 (4004 to 5122) | 10 357 (7059 to 14 807) | 17·8 (17·2 to 18·5)† | 0·1 (−0·4 to 0·5) | ||||
| Diabetes, urogenital, blood, and endocrine diseases | 2 927 330 (2 909 185 to 2 949 337) | 811 323 (769 165 to 854 588)* | 62 287 (44 312 to 84 848) | 21·1 (19·7 to 22·6)† | –0·3 (−1·4 to 0·8) | ||||
| Diabetes mellitus | 383 453 (352 588 to 414 576) | 20 828 (19 160 to 22 734) | 28 584 (19 534 to 39 575) | 23·6 (20·9 to 26·5)† | –1·2 (−3·3 to 1·2) | ||||
| Acute glomerulonephritis | 104 (90 to 117) | 1530 (1357 to 1729) | 5 (3 to 8) | 4·5 (2·4 to 6·8)† | –10·6 (−12·1 to −9·1)† | ||||
| Chronic kidney disease | 275 930 (252 442 to 300 414) | 21 329 (19 100 to 23 599) | 8772 (6600 to 11 104) | 30·4 (28·2 to 32·7)† | 3·8 (2·2 to 5·3)† | ||||
| Chronic kidney disease due to diabetes mellitus | 115 356 (101 848 to 130 636) | 8979 (7742 to 10 377) | 3695 (2768 to 4722) | 33·4 (30·7 to 36·0)† | 4·8 (3·1 to 6·7)† | ||||
| Chronic kidney disease due to hypertension | 50 097 (44 151 to 55 693) | 3626 (3131 to 4163) | 1680 (1200 to 2159) | 36·6 (33·4 to 40·3)† | 4·8 (2·6 to 7·3)† | ||||
| Chronic kidney disease due to glomerulonephritis | 49 615 (43 695 to 55 597) | 3893 (3261 to 4529) | 1479 (1093 to 1927) | 20·6 (17·6 to 23·8)† | –0·4 (−2·6 to 2·0) | ||||
| Chronic kidney disease due to other causes | 60 862 (52 600 to 69 124) | 4831 (4135 to 5526) | 1918 (1411 to 2502) | 28·0 (25·3 to 30·7)† | 4·0 (2·0 to 6·0)† | ||||
| Urinary diseases and male infertility | 146 155 (135 457 to 155 774) | 449 242 (412 808 to 488 929)* | 4140 (2727 to 5875) | 25·6 (24·3 to 27·0)† | –1·4 (−2·2 to −0·5)† | ||||
| Interstitial nephritis and urinary tract infections | 6913 (6201 to 7660) | 360 816 (325 242 to 399 931) | 228 (142 to 345) | 14·1 (12·0 to 16·1)† | 1·0 (−0·5 to 2·4) | ||||
| Urolithiasis | 2839 (2556 to 3162) | 75 218 (67 725 to 83 689) | 208 (140 to 286) | 21·5 (18·6 to 24·4)† | 0·3 (−1·9 to 2·4) | ||||
| Benign prostatic hyperplasia | 103 655 (91 930 to 115 236) | 13 208 (11 393 to 15 199) | 3384 (2178 to 4835) | 28·9 (27·5 to 30·3)† | –1·3 (−2·2 to −0·3)† | ||||
| Male infertility | 28 044 (22 703 to 35 076) | ·· | 165 (66 to 327) | 19·3 (15·7 to 22·6)† | 7·9 (4·9 to 10·6)† | ||||
| Other urinary diseases | ·· | ·· | 155 (103 to 216) | –3·3 (−4·9 to −1·7)† | –16·4 (−17·5 to −15·3)† | ||||
| Gynaecological diseases | 837 557 (822 589 to 852 391) | 300 826 (284 093 to 317 864)* | 10 195 (6918 to 14 656) | 11·9 (10·6 to 13·4)† | –2·2 (−3·3 to −1·1)† | ||||
| Uterine fibroids | 91 012 (82 090 to 100 488) | 9394 (8303 to 10 601) | 1375 (812 to 2218) | 19·0 (17·9 to 20·1)† | 0·2 (−0·5 to 1·0) | ||||
| Polycystic ovarian syndrome | 10 642 (8653 to 12 885) | 7651 (5518 to 10 179) | 94 (43 to 173) | 7·8 (6·4 to 9·4)† | –2·1 (−3·4 to −0·7)† | ||||
| Female infertility | 31 477 (19 472 to 49 304) | ·· | 180 (66 to 399) | 38·5 (29·4 to 49·5)† | 25·3 (17·7 to 34·8)† | ||||
| Endometriosis | 3554 (3197 to 3935) | 9262 (7894 to 10 960) | 332 (224 to 459) | 7·8 (5·2 to 10·7)† | –3·9 (−6·2 to −1·5)† | ||||
| Genital prolapse | 250 418 (222 236 to 278 690) | 16 608 (14 433 to 19 185) | 778 (382 to 1409) | 14·8 (13·7 to 15·9)† | –9·4 (−10·2 to −8·6)† | ||||
| Premenstrual syndrome | 454 296 (432 912 to 474 453) | 162 435 (153 441 to 171 301) | 3791 (2344 to 5813) | 9·2 (7·7 to 10·6)† | –2·0 (−3·3 to −0·8)† | ||||
| Other gynaecological diseases | 104 692 (93 190 to 116 476) | 95 475 (82 017 to 109 553) | 3645 (2430 to 5090) | 11·2 (8·8 to 14·2)† | –2·4 (−4·5 to 0·3) | ||||
| Haemoglobinopathies and haemolytic anaemias | 1 804 470 (1 782 496 to 1 828 051) | ·· | 6572 (4372 to 9566) | 12·8 (10·9 to 14·9)† | 1·8 (0·1 to 3·7)† | ||||
| Thalassaemias | 366 (343 to 394) | ·· | 23 (15 to 34) | –4·3 (−8·1 to −0·4)† | –8·5 (−12·2 to −4·8)† | ||||
| Thalassaemias trait | 287 107 (276 495 to 298 645) | ·· | 3280 (2157 to 4824) | 10·9 (8·0 to 13·9)† | –0·6 (−3·1 to 2·0) | ||||
| Sickle cell disorders | 3888 (3572 to 4470) | ·· | 317 (222 to 441) | 21·4 (17·1 to 26·0)† | 15·6 (11·5 to 19·9)† | ||||
| Sickle cell trait | 461 124 (418 742 to 516 943) | ·· | 1555 (1014 to 2283) | 16·8 (14·8 to 18·8)† | 7·3 (5·4 to 9·1)† | ||||
| G6PD deficiency | 331 513 (319 093 to 346 326) | ·· | 26 (18 to 36) | 14·5 (11·5 to 17·6)† | 3·1 (0·4 to 5·9)† | ||||
| G6PD trait | 865 927 (851 718 to 882 248) | ·· | 1 (0 to 1) | 17·6 (14·9 to 20·7)† | 4·9 (2·6 to 7·5)† | ||||
| Other haemoglobinopathies and haemolytic anaemias | 61 625 (59 671 to 63 634) | ·· | 1370 (912 to 1967) | 11·6 (9·4 to 14·3)† | –0·7 (−2·5 to 1·5) | ||||
| Endocrine, metabolic, blood, and immune disorders | 127 493 (119 899 to 135 715) | 17 569 (15 815 to 19 457) | 4020 (2721 to 5537) | 19·1 (17·4 to 20·8)† | –0·5 (−1·5 to 0·6) | ||||
| Musculoskeletal disorders | 1 270 630 (1 248 968 to 1 294 805) | 652 005 (591 746 to 719 811) | 137 832 (100 146 to 179 438) | 19·9 (18·7 to 21·0)† | –1·2 (−1·9 to −0·5)† | ||||
| Rheumatoid arthritis | 21 337 (19 466 to 23 612) | 1174 (1066 to 1298) | 4989 (3427 to 6604) | 28·8 (26·7 to 31·0)† | 3·7 (2·1 to 5·2)† | ||||
| Osteoarthritis | 301 567 (285 064 to 318 844) | 14 696 (13 728 to 15 682) | 16 283 (11 486 to 22 047) | 31·5 (30·7 to 32·2)† | 2·4 (1·9 to 3·0)† | ||||
| Low back and neck pain | 748 081 (721 756 to 766 729) | 313 434 (281 503 to 347 952) | 86 584 (61 335 to 113 628) | 19·3 (17·7 to 20·7)† | –1·3 (−2·4 to −0·5)† | ||||
| Low back pain | 511 048 (457 208 to 572 056) | 250 277 (220 585 to 283 681) | 57 648 (40 820 to 75 877) | 18·0 (16·0 to 20·1)† | –2·0 (−3·6 to −0·9)† | ||||
| Neck pain | 290 524 (254 815 to 332 009) | 63 157 (55 205 to 74 075) | 28 936 (19 578 to 40 543) | 21·9 (19·9 to 24·0)† | 0·1 (−1·3 to 1·4) | ||||
| Gout | 33 977 (30 617 to 37 923) | 6435 (5666 to 7248) | 1071 (742 to 1455) | 26·2 (24·3 to 27·9)† | –0·1 (−1·3 to 1·1) | ||||
| Other musculoskeletal disorders | 337 859 (289 444 to 390 647) | 316 267 (266 448 to 375 370) | 28 904 (19 554 to 40 812) | 14·4 (11·5 to 17·2)† | –3·5 (−5·7 to −1·6)† | ||||
| Other non-communicable diseases | 5 292 032 (5 257 502 to 5 326 591) | 14 922 120 (14 136 832 to 15 793 314)* | 150 066 (102 792 to 212 136) | 16·7 (16·0 to 17·2)† | –0·6 (−1·0 to −0·2)† | ||||
| Congenital anomalies | 82 890 (78 027 to 87 071) | ·· | 9723 (6979 to 12 887) | 9·1 (7·5 to 10·6)† | –1·5 (−3·0 to −0·2)† | ||||
| Neural tube defects | 5782 (5232 to 6393) | ·· | 1723 (1220 to 2299) | 14·6 (12·1 to 17·4)† | 3·0 (0·8 to 5·6)† | ||||
| Congenital heart anomalies | 15 377 (13 712 to 17 128) | ·· | 755 (332 to 1284) | 8·5 (6·3 to 10·4)† | –0·9 (−2·9 to 0·8) | ||||
| Orofacial clefts | 3590 (3230 to 3967) | ·· | 46 (30 to 67) | 3·5 (0·7 to 6·3)† | –7·3 (−9·8 to −4·8)† | ||||
| Down's syndrome | 2031 (1776 to 2314) | ·· | 185 (124 to 258) | 8·3 (5·9 to 10·7)† | –1·1 (−3·4 to 1·1) | ||||
| Turner syndrome | 2719 (2378 to 3089) | ·· | 47 (22 to 76) | 6·9 (3·2 to 10·4)† | –1·0 (−4·3 to 2·1) | ||||
| Klinefelter syndrome | 3043 (2641 to 3482) | ·· | 17 (8 to 32) | 9·0 (6·2 to 11·7)† | 0·0 (−2·5 to 2·5) | ||||
| Other chromosomal abnormalities | 4310 (3734 to 4977) | ·· | 494 (345 to 665) | 4·3 (2·2 to 6·4)† | 1·5 (−0·6 to 3·6) | ||||
| Congenital musculoskeletal and limb anomalies | 10 812 (9 960 to 11 711) | ·· | 1536 (1056 to 2113) | 13·2 (11·1 to 15·2)† | –0·1 (−1·9 to 1·7) | ||||
| Urogenital congenital anomalies | 7172 (6493 to 7894) | ·· | 189 (112 to 298) | 1·8 (0·1 to 3·1)† | –3·5 (−4·8 to −2·4)† | ||||
| Digestive congenital anomalies | 9711 (8741 to 10 731) | ·· | 427 (280 to 610) | 9·0 (6·1 to 11·9)† | –3·2 (−5·8 to −0·6)† | ||||
| Other congenital anomalies | 34 984 (24 584 to 49 402) | ·· | 4302 (2844 to 6310) | 6·8 (4·4 to 9·6)† | –3·9 (−6·1 to −1·4)† | ||||
| Skin and subcutaneous diseases | 2 266 315 (2 242 994 to 2 285 332) | 5 074 605 (4 838 566 to 5 335 844) | 54 635 (36 830 to 79 320) | 10·7 (10·2 to 11·3)† | 1·2 (0·9 to 1·5)† | ||||
| Dermatitis | 306 359 (290 041 to 324 193) | 430 376 (398 274 to 462 932) | 11 210 (6 714 to 18 218) | 11·6 (10·8 to 12·4)† | 1·1 (0·3 to 1·8)† | ||||
| Psoriasis | 65 135 (62 708 to 67 812) | 8170 (7861 to 8478) | 5643 (4040 to 7377) | 21·7 (20·8 to 22·6)† | 4·2 (3·6 to 5·0)† | ||||
| Cellulitis | 3018 (2842 to 3210) | 61 333 (58 280 to 64 556) | 170 (112 to 244) | 14·0 (12·2 to 16·0)† | –0·5 (−1·9 to 1·0) | ||||
| Pyoderma | 21 020 (20 491 to 21 564) | 474 384 (461 024 to 488 662) | 117 (47 to 243) | 22·8 (21·9 to 23·6)† | 5·2 (4·4 to 5·8)† | ||||
| Scabies | 146 785 (127 773 to 170 009) | 454 671 (392 690 to 529 184) | 3788 (2104 to 6029) | 3·2 (1·8 to 4·6)† | –5·4 (−6·2 to −4·8)† | ||||
| Fungal skin diseases | 626 700 (568 967 to 690 267) | 2 098 743 (1 884 346 to 2 337 325) | 3509 (1403 to 7271) | 18·0 (17·0 to 19·1)† | 2·5 (2·2 to 2·9)† | ||||
| Viral skin diseases | 193 171 (184 773 to 201 619) | 276 755 (263 471 to 290 018) | 5915 (3674 to 8828) | 9·0 (8·5 to 9·5)† | –0·1 (−0·5 to 0·2) | ||||
| Acne vulgaris | 614 771 (560 634 to 672 878) | 429 822 (361 790 to 521 114) | 15 836 (10 644 to 22 843) | 5·1 (4·3 to 5·8)† | 2·1 (1·5 to 2·6)† | ||||
| Alopecia areata | 15 416 (14 906 to 15 948) | 27 247 (26 347 to 28 203) | 504 (323 to 760) | 12·8 (11·8 to 13·9)† | –1·3 (−2·2 to −0·5)† | ||||
| Pruritus | 66 780 (59 262 to 74 868) | 53 046 (47 751 to 59 503) | 709 (330 to 1 299) | 18·2 (16·7 to 19·8)† | 1·3 (0·8 to 1·8)† | ||||
| Urticaria | 67 060 (59 299 to 77 018) | 119 403 (105 497 to 135 993) | 4030 (2576 to 5745) | 9·4 (8·3 to 10·5)† | –0·3 (−0·8 to 0·3) | ||||
| Decubitus ulcer | 1836 (1660 to 2017) | 6722 (6040 to 7456) | 290 (203 to 388) | 27·0 (24·2 to 29·6)† | –0·8 (−2·8 to 1·0) | ||||
| Other skin and subcutaneous diseases | 532 790 (519 540 to 545 725) | 633 932 (616 730 to 651 838) | 2913 (1409 to 5325) | 25·3 (24·8 to 25·7)† | 4·5 (4·3 to 4·7)† | ||||
| Sense organ diseases | 1 843 201 (1 825 393 to 1 861 436) | 708 004 (667 844 to 753 886)* | 66 702 (46 534 to 92 392) | 21·7 (20·7 to 22·5)† | –1·9 (−2·6 to −1·3)† | ||||
| Glaucoma | 4761 (3973 to 5573) | ·· | 461 (311 to 642) | 35·7 (33·7 to 38·0)† | 2·1 (0·7 to 3·6)† | ||||
| Cataract | 83 628 (73 800 to 93 905) | ·· | 5789 (4 135 to 7 915) | 31·0 (29·4 to 32·6)† | 0·0 (−1·2 to 1·1) | ||||
| Macular degeneration | 6147 (5111 to 7401) | ·· | 409 (278 to 556) | 37·5 (34·7 to 40·4)† | 2·7 (0·7 to 4·7)† | ||||
| Refraction and accommodation disorders | 854 299 (822 109 to 885 545) | ·· | 14 972 (9 341 to 23 362) | 14·9 (13·7 to 15·9)† | –4·9 (−5·8 to −4·3)† | ||||
| Age-related and other hearing loss | 1 271 675 (1 210 237 to 1 337 731) | ·· | 36 288 (25 342 to 50 894) | 22·3 (20·4 to 24·0)† | –1·7 (−2·9 to −0·6)† | ||||
| Other vision loss | 29 249 (25 873 to 32 927) | ·· | 2241 (1578 to 3016) | 26·1 (23·9 to 28·1)† | 0·7 (−0·8 to 2·0) | ||||
| Other sense organ diseases | 210 697 (195 303 to 225 565) | 708 004 (667 844 to 753 886) | 6542 (4132 to 9828) | 23·8 (23·1 to 24·4)† | 0·9 (0·6 to 1·3)† | ||||
| Oral disorders | 3 583 600 (3 475 812 to 3 657 885) | 9 139 511 (8 388 756 to 9 926 992)* | 19 006 (11 587 to 29 630) | 22·2† (21·2 to 23·3) | –0·2 (−0·7 to 0·2) | ||||
| Caries of deciduous teeth | 486 095 (398 110 to 573 474) | 1 762 264 (1 264 051 to 2 391 119) | 127 (56 to 249) | 6·8 (4·5 to 8·5)† | 0·2 (−1·9 to 1·8) | ||||
| Caries of permanent teeth | 2 435 850 (2 288 064 to 2 586 461) | 7 263 992 (6 715 107 to 7 835 458) | 1708 (760 to 3325) | 8·7 (8·0 to 9·4)† | –4·2 (−4·8 to −3·6)† | ||||
| Periodontal disease | 750 847 (633 975 to 874 077) | 89 840 (74 128 to 106 716) | 4898 (1947 to 10 209) | 25·8 (24·7 to 26·8)† | 2·3 (1·8 to 2·9)† | ||||
| Edentulism and severe tooth loss | 302 342 (263 801 to 339 035) | 23 414 (19 894 to 27 222) | 8338 (5467 to 11 760) | 27·2 (26·0 to 28·4)† | –0·9 (−1·6 to −0·3)† | ||||
| Other oral disorders | 134 457 (128 968 to 140 248) | ·· | 3935 (2427 to 5908) | 15·2 (14·6 to 15·8)† | 0·0 (−0·3 to 0·3) | ||||
| Injuries | 1 492 784 (1 413 602 to 1 584 568) | 619 651 (592 467 to 648 150)* | 55 358 (37 181 to 78 689) | 22·1 (21·0 to 23·2)† | 2·0 (1·2 to 2·6)† | ||||
| Transport injuries | 241 194 (225 137 to 258 446) | 75 419 (68 548 to 82 688) | 12 345 (8227 to 17 658) | 25·6 (24·5 to 26·6)† | 4·1 (3·3 to 4·8)† | ||||
| Road injuries | 194 515 (182 106 to 208 390) | 65 536 (58 946 to 72 433) | 9983 (6650 to 14 255) | 28·1 (27·2 to 29·0)† | 5·5 (4·9 to 6·1)† | ||||
| Pedestrian road injuries | 43 124 (38 450 to 48 872) | 11 342 (9709 to 13 303) | 2261 (1511 to 3222) | 28·7 (27·1 to 30·1)† | 5·8 (4·9 to 6·7)† | ||||
| Cyclist road injuries | 38 983 (33 088 to 45 660) | 15 288 (12 715 to 17 993) | 1873 (1238 to 2710) | 31·0 (30·1 to 31·8)† | 8·1 (7·5 to 8·6)† | ||||
| Motorcyclist road injuries | 46 084 (39 635 to 55 732) | 11 346 (9534 to 13 518) | 2336 (1555 to 3342) | 29·5 (28·3 to 30·6)† | 7·3 (6·5 to 8·0)† | ||||
| Motor vehicle road injuries | 51 784 (43 776 to 59 354) | 20 993 (18 156 to 23 790) | 2821 (1895 to 3991) | 20·9 (20·0 to 21·8)† | –1·0 (−1·8 to −0·2)† | ||||
| Other road injuries | 14 539 (12 463 to 17 017) | 6566 (5217 to 8267) | 693 (457 to 1 014) | 48·2 (46·5 to 49·7)† | 22·9 (21·9 to 23·8)† | ||||
| Other transport injuries | 46 680 (39 471 to 54 858) | 9884 (8552 to 11 480) | 2362 (1595 to 3372) | 15·8 (14·2 to 17·5)† | –1·5 (−2·8 to −0·3)† | ||||
| Unintentional injuries | 1 127 878 (1 053 751 to 1 211 481) | 510 685 (484 967 to 539 046) | 37 696 (25 530 to 53 091) | 22·9 (21·8 to 23·8)† | 2·3 (1·5 to 2·9)† | ||||
| Falls | 474 230 (419 318 to 528 012) | 208 272 (189 203 to 229 948) | 18 946 (13 288 to 26 043) | 26·7 (25·8 to 27·6)† | 3·4 (2·6 to 4·1)† | ||||
| Drowning | 4684 (4129 to 5324) | 846 (763 to 938) | 233 (153 to 336) | 4·9 (2·9 to 6·9)† | –12·3 (−13·7 to −11·0)† | ||||
| Fire, heat, and hot substances | 102 124 (87 477 to 121 846) | 10 997 (9148 to 12 675) | 2455 (1601 to 3666) | 18·6† (17·0 to 19·9) | 1·0 (−0·1 to 1·8) | ||||
| Poisonings | 3526 (2984 to 4133) | 4697 (3858 to 5639) | 298 (192 to 437) | 25·8 (24·5 to 27·2)† | 8·9 (7·8 to 10·1)† | ||||
| Exposure to mechanical forces | 197 786 (168 555 to 241 945) | 67 906 (59 032 to 76 818) | 4412 (2854 to 6440) | 24·4 (23·2 to 25·5)† | 3·9 (3·2 to 4·5)† | ||||
| Unintentional firearm injuries | 7091 (5867 to 8629) | 1429 (1052 to 1893) | 228 (146 to 341) | 23·5† (22·3 to 24·4) | 4·0 (3·3 to 4·5)† | ||||
| Unintentional suffocation | 9395 (7248 to 12 049) | 1804 (1347 to 2370) | 282 (174 to 438) | 11·8 (10·3 to 13·5)† | –2·8 (−3·7 to −1·8)† | ||||
| Other exposure to mechanical forces | 181 300 (153 213 to 224 295) | 64 673 (56 323 to 73 039) | 3 901 (2 536 to 5 696) | 25·5 (24·2 to 26·6)† | 4·5 (3·7 to 5·1)† | ||||
| Adverse effects of medical treatment | 2924 (2328 to 3567) | 38 245 (34 405 to 42 385) | 390 (246 to 580) | 11·8 (10·2 to 13·5)† | –4·4 (−6·0 to −2·8)† | ||||
| Animal contact | 53 654 (47 673 to 61 282) | 65 550 (56 597 to 74 579) | 1667 (1126 to 2315) | 11·0 (9·7 to 12·2)† | –4·0 (−4·9 to −3·2)† | ||||
| Venomous animal contact | 24 759 (20 818 to 29 310) | 31 691 (25 886 to 38 600) | 1204 (813 to 1684) | 11·7 (10·4 to 13·1)† | –2·4 (−3·5 to −1·3)† | ||||
| Non-venomous animal contact | 28 894 (24 541 to 34 730) | 33 859 (27 953 to 40 468) | 463 (303 to 708) | 9·1 (7·2 to 10·8)† | –7·9 (−9·4 to −6·7)† | ||||
| Foreign body | 54 797 (45 419 to 63 613) | 35 172 (30 752 to 40 749) | 2040 (1308 to 3022) | 16·6 (14·9 to 18·5)† | 0·8 (−0·4 to 2·1) | ||||
| Pulmonary aspiration and foreign body in airway | 26 682 (20 450 to 35 018) | 10 801 (9 348 to 12 717) | 1124 (719 to 1683) | 12·4 (10·8 to 14·1)† | –2·1 (−3·3 to −0·9)† | ||||
| Foreign body in eyes | 3168 (1880 to 4640) | 15 443 (11 951 to 20 505) | 186 (100 to 310) | 26·8 (24·1 to 30·1)† | 8·2 (6·3 to 10·3)† | ||||
| Foreign body in other body part | 24 947 (20 403 to 31 426) | 8929 (7508 to 10 562) | 730 (468 to 1 083) | 21·2 (19·5 to 23·1)† | 3·8 (2·6 to 5·0)† | ||||
| Environmental heat and cold exposure | 74 104 (63 212 to 86 149) | 19 591 (16 473 to 23 142) | 2756 (1829 to 3963) | 18·9 (17·1 to 20·9)† | 0·7 (−0·8 to 2·1) | ||||
| Other unintentional injuries | 160 048 (131 378 to 191 818) | 59 409 (51 226 to 68 804) | 4500 (2972 to 6571) | 20·5 (19·6 to 21·3)† | 1·5 (0·7 to 2·3)† | ||||
| Self-harm and interpersonal violence | 230 043 (210 093 to 252 561) | 32 470 (28 739 to 36 265)* | 3884 (2672 to 5491) | 9·3 (8·3 to 10·4)† | –5·8 (−6·3 to −5·4)† | ||||
| Self-harm | 11 924 (10 160 to 13 744) | 6893 (6130 to 7759) | 528 (342 to 764) | 10·0 (8·9 to 11·2)† | –9·4 (−10·1 to −8·8)† | ||||
| Self-harm by firearm | 380 (326 to 439) | 98 (61 to 149) | 13 (8 to 20) | 3·6 (1·9 to 5·4)† | –12·5 (−13·8 to −11·2)† | ||||
| Self-harm by other specified means | 11 544 (9770 to 13 356) | 6795 (6037 to 7607) | 515 (333 to 744) | 10·2 (9·1 to 11·3)† | –9·3 (−10·1 to −8·7)† | ||||
| Interpersonal violence | 218 118 (197 726 to 240 339) | 25 577 (22 086 to 29 230)* | 3356 (2325 to 4709) | 9·2 (8·1 to 10·4)† | –5·2 (−5·7 to −4·8)† | ||||
| Assault by firearm | 2899 (2388 to 3485) | 710 (560 to 897) | 104 (66 to 156) | 14·9 (13·9 to 16·0)† | –3·6 (−4·3 to −2·9)† | ||||
| Assault by sharp object | 15 012 (12 272 to 17 936) | 5603 (4397 to 6946) | 412 (269 to 601) | 10·5 (9·0 to 12·0)† | –6·6 (−7·6 to −5·7)† | ||||
| Sexual violence | 160 421 (141 228 to 181 452) | ·· | 1366 (917 to 1946) | 3·5 (2·2 to 4·8)† | –5·5 (−6·2 to −4·9)† | ||||
| Assault by other means | 39 786 (33 335 to 48 036) | 19 263 (16 510 to 22 244) | 1474 (988 to 2129) | 14·3 (13·4 to 15·1)† | –4·7 (−5·4 to −4·2)† | ||||
| Forces of nature, conflict and terrorism, and executions and police conflict | 54 091 (34 969 to 76 753) | 1077 (759 to 1328)* | 1433 (510 to 3006) | 12·5 (5·0 to 18·2)† | –1·1 (−7·3 to 3·8) | ||||
| Exposure to forces of nature | 7571 (4293 to 11 602) | 377 (231 to 534) | 260 (71 to 610) | 32·2 (17·0 to 39·5)† | 16·4 (3·5 to 23·0)† | ||||
| Conflict and terrorism | 40 684 (24 541 to 61 725) | ·· | 1100 (432 to 2206) | 10·8 (3·5 to 18·0)† | –2·4 (−8·5 to 3·9) | ||||
| Executions and police conflict | 5836 (1906 to 9042) | 700 (410 to 883) | 131 (28 to 344) | –6·7 (−11·2 to −2·3)† | –20·0 (−23·6 to −16·3)† | ||||
| Impairments | ·· | ·· | ·· | ·· | ·· | ||||
| Anaemia | 2 042 728 (1 979 003 to 2 110 037) | ·· | 61 649 (41 483 to 86 424) | 9·2 (6·4 to 11·2)† | –2·2 (−4·8 to −0·3)† | ||||
| Developmental intellectual disability | 196,243 (150 264 to 242 144) | ·· | 19 925 (14 584 to 26 434) | 8·3 (6·5 to 10·7)† | –1·8 (−3·4 to 0·4) | ||||
| Epilepsy | 45 926 (39 942 to 54 564) | ·· | 15 392 (11 594 to 20 379) | 10·5 (2·5 to 19·1)† | –0·6 (−7·7 to 7·0) | ||||
| Guillain-Barré syndrome | 65 (52 to 82) | ·· | 19 (12 to 28) | 16·7 (14·1 to 19·5)† | 0·5 (−0·4 to 1·2) | ||||
| Hearing loss | 1 390 482 (1 329 902 to 1 455 762) | ·· | 42 630 (30 019 to 59 264) | 18·8 (17·0 to 20·4)† | –2·5 (−3·6 to −1·5)† | ||||
| Heart failure | 63 609 (56 944 to 71 388) | ·· | 7783 (5857 to 9788) | 30·2 (28·8 to 31·6)† | –0·6 (−1·6 to 0·3) | ||||
| Infertility | 117 207 (94 952 to 145 048) | ·· | 719 (310 to 1400) | 18·7 (15·4 to 21·6)† | 7·0 (4·3 to 9·4)† | ||||
| Pelvic inflammatory disease | 4099 (3533 to 4740) | ·· | 535 (360 to 743) | 7·8 (5·5 to 10·1)† | –5·5 (−7·5 to −3·6)† | ||||
| Vision loss | 1 009 472 (969 235 to 1 047 829) | ·· | 28 748 (20 342 to 40 240) | 20·4 (19·1 to 22·0)† | –1·3 (−2·4 to 0·8) | ||||
We did not calculate incidence for the nine impairments, certain neglected tropical diseases, and causes with only birth prevalence. Blank cells mean that no estimate is available. Cells with zeros indicate an estimate smaller than 500 as the table presents prevalence and incidence counts in thousands. To download the data in this table, please visit the Global Health Data Exchange (GHDx) at: http://ghdx.healthdata.org/node/311084.
*
Incidence for aggregate causes represents the sum of the incidence of the causes below the aggregate.
†
Percentage changes that are statistically significant.
‡
Incidence of HIV/AIDS represents new infections of HIV only and does not include new infections of tuberculosis in HIV positive cases.
§
Incidence estimates for stroke represent first-ever stroke only. YLDs=years lived with disability.