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. 2017 Sep 19;7:11878. doi: 10.1038/s41598-017-12183-z

Figure 3.

Figure 3

Systemic treatment with bumetanide during early development had no effect on body weight or normal behaviors. (A) Experimental timeline of bumetanide treatment and behavioral tests. (B) Sucrose preference in the SPT. (C) Total distance travelled in 1 h in the open field test (OFT). (D) Time spent in the central area in the OFT. (E) Body weight of bumetanide and vehicle rats. The data are expressed as mean ± SEM. n = 35–40 per group (13–15 females, 20–23 males).*p < 0.05, compared with vehicle group.