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. 2017 Sep 19;7:11906. doi: 10.1038/s41598-017-12106-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Simultaneous display of BG, food intake, and activity from days 18–20 in GK rats. Upper panel: BG as assessed by glucose telemetry. Error bars every 6 h indicate either the upper or lower s.e.m. Middle panel: Food intake measured every hour. Lower panel: Activity measured every hour. #Reactions to short-term handling stress, such as blood collection and measurement of body weight. Values are expressed as mean ± s.e.m. n = 3–4 per group.