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. 2017 Sep 19;7:11906. doi: 10.1038/s41598-017-12106-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of ipragliflozin on body weight, liver weight, epididymal fat weight, and glycogen content in liver in normal and GK rats. (a) Percentage change of body weight from baseline. (b) Liver weight. (c) Epididymal fat weight. (d) Glycogen content in liver. (e) Histological findings with periodic acid-Schiff staining of the liver. Scale bars, 100 μm. **P < 0.05 vs. Wistar + vehicle. ^† P < 0.05, ^†† P < 0.01 vs. GK + vehicle. Values are expressed as mean ± s.e.m. n = 4–6 per group.