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. 2017 Sep 15;11:290. doi: 10.3389/fncel.2017.00290

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Copyright © 2017 Wu, Mo, Kou, Liu, Lv, Lei and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BMEC increase miniature excitatory postsynaptic currents (mEPSC) frequency. (A) Example traces from neurons cultured alone, co-cultured with BMEC or treated with B-CM showing mEPSC recorded in the presence of 1 μM TTX and 10 μM picrotoxin at −65 mV. Scale bar is shown in the right. (B,C) Cumulative probability plots of interevent interval and the quantification of mEPSC frequency are shown. (D,E) Cumulative probability plot of mEPSC amplitude and the quantification of mEPSC amplitude are shown (n = 13 per condition. *p < 0.05; **p < 0.01).