Table 1.
List of included studies on the effect of resistance exercise on mitochondrial adaptations in healthy subjects.
| Reference | Duration and frequency | Mitochondrial endpoints | Comments | ||
|---|---|---|---|---|---|
| Biogenesis | Content | Function | |||
| HIGH-LOAD RESISTANCE EXERCISE—ACUTE STUDIES | |||||
| Wilkinson et al., 2008* | Single bout | Unaccustomed-RE ↑ | N/A | N/A | Dietary status: fed (protein, carbohydrate, fat) |
| Accustomed-RE: ↔ | |||||
| Donges et al., 2012 | Single bout | ↑ | N/A | N/A | Dietary status: fed (protein) |
| HIGH-LOAD RESISTANCE TRAINING—CHRONIC STUDIES | |||||
| MacDougall et al., 1979 | 24 weeks, 3 days week−1 | N/A | ↓ | N/A | |
| Luthi et al., 1986 | 6 weeks, 3 days week−1 | N/A | ↓ | N/A | |
| Tesch et al., 1990 | 12 weeks, 3 days week−1 | N/A | ↔ | N/A | Non-exercise control group included |
| Wang et al., 1993 | 18 weeks, 2 days week−1 | N/A | ↔ | N/A | |
| Ploutz et al., 1994 | 9 weeks, 2 days week−1 | N/A | ↔ | N/A | |
| Chilibeck et al., 1999 | 12 weeks, 3 days week−1 | N/A | ↓ | N/A | Non-exercise control group included |
| Green et al., 1999 | 12 weeks, 3 days week−1 | N/A | ↔ | N/A | |
| Bell et al., 2000 | 12 weeks, 3 days week−1 | N/A | ↔ | N/A | Non-exercise control group included |
| Tang et al., 2006 | 12 weeks, 5 days week−1 | N/A | ↑ | N/A | |
| Wilkinson et al., 2008* | 10 weeks, 2-3 days week−1 | N/A | ↔ | N/A | |
| Pesta et al., 2011 | 10 weeks, 3 days week−1 | N/A | ↔ | ↑ | HRR: permeabilized myofibers |
| Salvadego et al., 2013 | Cross-sectional design | N/A | RE-trained vs. untrained: ↔ | RE-trained vs. untrained: ↑ | HRR: permeabilized myofibers |
| Kon et al., 2014 | 8 weeks, 2 days week−1 | N/A | ↓ | N/A | |
| Irving et al., 2015 | 8 weeks, 4 days week−1 | N/A | Young: ↔ | Young: ↔ | Non-exercise control group included |
| Aging: ↔ | Aging: ↔ | HRR: isolated mitochondria | |||
| Porter et al., 2015 | 12 weeks, 2 days week−1 | N/A | ↔ | ↑ | HRR: permeabilized myofibers |
| Robinson et al., 2017 | 12 weeks, 4 days week−1 | Young: ↔ | Young: ↑ | Young: ↔ | Non-exercise control group included |
| Aging: ↑ | Aging: ↑ | Aging: ↔ | HRR: isolated mitochondria | ||
| Individual mitochondrial protein content evaluated by proteomics | |||||
| LOW-LOAD RESISTANCE EXERCISE—ACUTE STUDIES | |||||
| Burd et al., 2012 | Single bout | ↑ | N/A | N/A | Dietary status: fed (protein) |
RE, resistance exercise; HRR, high resolution respirometry;
same paper.