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. 2017 Sep 19;7:11832. doi: 10.1038/s41598-017-12150-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Flow cytometry and comparative graph: apoptosis/necrosis detection of HEK-293 cells (nucleolin⁻) using flow cytometry. (1) ALGDG2-Iohexol, (2) Apt-ALGDG2-Iohexol (3) Free Iohexol. (C) Controls: (right) treated unstained and (left) untreated unstained. Comparative graph shows the effect of three different compounds on the HEK-293 cells. Data are presented as mean ± SEM. Based on statistical analyses, all three components have significant differences in total apoptotic cells from the untreated control cells (p value < 0.05).