Table 2.

Proteins from mouse hypothalamus, identified by MS analysis, associate with mouse PR in a ligand-dependent manner

Synaptic structure and function	UniProt symbol	Uniprot ID	PR-A (R5020/no ligand)	PR-B (R5020/no ligand)
Synapsin-I	SYN1	O88935	+	+
Synapsin-II	SYN2	Q64332	+	+
Synapsin-III	SYN3	Q8JZP2		+
Synaptogyrin-III	SNG3	Q8R191	+
α-Synuclein	SYUA	O55042		+
Septin-5	SEPTM5	Q9Z2Q6		+
Desmoglein-4	Desmoglein-4	Q7TMD7	+
Desmoplakin	DESP	E9Q557	+
Junction plakoglobin	PLAK	Q02257	+
Leucine-rich repeat-containing protein 15	LGR4	A2ARI4	+
Hemoglobin subunit β-1	HBB1	P02088	+
β-Actin-like protein 2	ACTBL	Q8BFZ3		+
Tubulin α-1A chain	TBA1A	P68369		+
Tubulin α-1B chain	TBA1B	P05213		+
Tubulin β-2A chain	TBB2A	Q7TMM9	+	+
Tubulin β-3 chain	TBB3	Q9ERD7	+
Tubulin β-4A chain	TBB4A	Q9D6F9	+
Tubulin β-4B chain	TBB4B	P68372	+
Tubulin β-5 chain	TBB5	P99024	+	+
Tubulin β-6 chain	TBB6	Q922F4		+
Signal transduction
Mitogen-activated protein kinase 1	MK01	P63085		+
14-3-3 protein ζ/δ	1433Z	P63101		+
Rab GDP dissociation inhibitor β	GDIB	Q61598		+
Transcription
Elongation factor 1β	TIF1B	Q62318	+
Histone H4	H4	P62806	+
Brain acid soluble protein 1	A4	P12023		+
Heterogeneous nuclear ribonucleoprotein D-like	HNRDL	Q9Z130		+
Heterogeneous nuclear ribonucleoprotein U-like protein 1	HNRL1	Q8VDM6		+
Probable ATP-dependent RNA helicase DDX5	DDX5	Q61656		+
Translation
26S protease regulatory subunit 6A	PRS6A	O88685		+
40S ribosomal protein S9	RS9	Q6ZWN5		+
Metabolism
Creatine kinase B-type	KCRB	Q04447	+
Phytanoyl-CoA hydroxylase-interacting protein-like	PHIPL	Q8BGT8	+

Proteins associate with PR with R5020/no ligand at a ratio ≥2 and p < 0.05. Table 2-1 shows proteins identified by MS that associate with PR in the absence of ligand.