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. 2017 Feb 16;25(6):911–920. doi: 10.1016/j.jsps.2017.02.007

Table 1.

The kinetic parameters for the vancomycin release from the systems studied.

Sample Zero-order
First-order
Higuchi
Korsmeyer-Peppas
k R2 k R2 k R2 k R2
HNT_APTS 0.008 ± 0.006 0.853 0.001 ± 0.001 0.997 1.943 ± 0.225a 0.979a 3.885 ± 0.563a 0.956a
0.971 ± 0.530 0.866 5.054 ± 0.512 0.936
HNT_APTS in Alginate 0.021 ± 0.004 0.848 0.001 ± 0.001 0.960 1.107 ± 0.116a 0.995a 1.435 ± 0.268a 0.980a
1.193 ± 0.124 0.997 1.206 ± 0.095 0.987
HNT_APTS in Gelatin/Alginate 0.015 ± 0.009 0.763 >0.001 ± 0.001 0.940 0.948 ± 0.207a 0.986a 1.058 ± 0.280a 0.969a
0.950 ± 0.238 0.995 1.224 ± 0.345 0.974
a

Values obtained considering only drug released <60%.