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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2017 Apr 26;99(2):325–333. doi: 10.1016/j.ijrobp.2017.04.024

Table 1.

Normal tissue complication probabilities for grade 2+ radiation pneumonitis are presented for NTCP models that account for both dose to functional sub-volumes and dose to the total lung.

Grade 2+ Toxicity
Dose Metrics for NTCP Model Mean Toxicity Probability – Clinical Plan Mean Toxicity Probability – Functional Plan Absolute Reduction
fV5Gy + V5Gy 44.9% 35.8% 9.1%
fV10Gy + V10Gy 42.2% 31.8% 10.4%
fV20Gy + V20Gy 39.9% 33.4% 6.5%
fV30Gy + V30Gy 39.7% 33.2% 6.4%
fMLD + MLD 34.8% 34.1% 0.6%