Table 2.
Normal tissue complication probabilities for grade 3+ radiation pneumonitis are presented for NTCP models that account for both dose to functional sub-volumes and dose to the total lung.
| Grade 3+ Toxicity | |||
|---|---|---|---|
| Dose Metrics for NTCP Model | Mean Toxicity Probability – Clinical Plan | Mean Toxicity Probability – Functional Plan | Absolute Reduction |
| fV5Gy + V5Gy | 23.2% | 19.0% | 4.2% |
| fV10Gy + V10Gy | 22.2% | 17.5% | 4.7% |
| fV20Gy + V20Gy | 20.2% | 16.6% | 3.7% |
| fV30Gy + V30Gy | 20.1% | 15.9% | 4.2% |
| fMLD + MLD | 17.7% | 17.7% | 0.0% |